Robert E Rhoads
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Explore the profile of Robert E Rhoads including associated specialties, affiliations and a list of published articles.
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47
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Recent Articles
11.
Chiluiza D, Bargo S, Callahan R, Rhoads R
J Biol Chem
. 2011 Jul;
286(36):31288-96.
PMID: 21737453
Integration of mouse mammary tumor virus (MMTV) at the common integration site Int6 occurs in the gene encoding eIF3e, the p48 subunit of translation initiation factor eIF3. Integration is at...
12.
Senkovich O, Yin J, Ekshyyan V, Conant C, Traylor J, Adegboyega P, et al.
Infect Immun
. 2011 May;
79(8):3106-16.
PMID: 21576328
Helicobacter pylori persistently colonizes humans, causing gastritis, ulcers, and gastric cancer. Adherence to the gastric epithelium has been shown to enhance inflammation, yet only a few H. pylori adhesins have...
13.
Su W, Slepenkov S, Grudzien-Nogalska E, Kowalska J, Kulis M, Zuberek J, et al.
RNA
. 2011 Mar;
17(5):978-88.
PMID: 21447710
Decapping is an essential step in multiple pathways of mRNA degradation. Previously, we synthesized mRNAs containing caps that were resistant to decapping, both to dissect the various pathways for mRNA...
14.
Korneeva N, Soung Y, Kim H, Giordano A, Rhoads R, Gram H, et al.
Mol Cancer Res
. 2010 Nov;
8(12):1571-8.
PMID: 21047768
It was previously shown that integrin α6β4 contributes to translation of cancer-related mRNAs such as VEGF via initiation factor eIF4E. In this study, we found that integrin α6β4 regulates the...
15.
Strenkowska M, Kowalska J, Lukaszewicz M, Zuberek J, Su W, Rhoads R, et al.
New J Chem
. 2010 Aug;
34(5):993-1007.
PMID: 20711517
We describe the chemical synthesis and preliminary biophysical and biochemical characterization of a series of mRNA 5' end (cap) analogs designed as reagents for obtaining mRNA molecules with augmented translation...
16.
Song A, Labella S, Korneeva N, Keiper B, Aamodt E, Zetka M, et al.
J Cell Sci
. 2010 Jun;
123(Pt 13):2228-37.
PMID: 20530576
Caenorhabditis elegans expresses five family members of the translation initiation factor eIF4E whose individual physiological roles are only partially understood. We report a specific role for IFE-2 in a conserved...
17.
18.
Rhoads R
J Biol Chem
. 2009 Feb;
284(25):16711-16715.
PMID: 19237539
Eukaryotic initiation factor 4E (eIF4E) has long been known as the cap-binding protein that participates in recruitment of mRNA to the ribosome. A number of recent advances have not only...
19.
Okade H, Fujita Y, Miyamoto S, Tomoo K, Muto S, Miyoshi H, et al.
J Biochem
. 2009 Jan;
145(3):299-307.
PMID: 19122207
To investigate the binding specificity of turnip mosaic virus (TuMV) viral protein-genome linked (VPg) with translation initiation factor 4E, we evaluated here the kinetic parameters for the interactions of human...
20.
Slepenkov S, Korneeva N, Rhoads R
J Biol Chem
. 2008 Jul;
283(37):25227-25237.
PMID: 18614538
Interaction of the mRNA cap with the translational machinery is a critical and early step in the initiation of protein synthesis. To better understand this process, we determined kinetic constants...