Molecular Cancer Research : Mcr
Overview
Molecular Cancer Research (MCR) is a renowned scientific journal that focuses on cutting-edge research in the field of cancer biology and molecular oncology. It publishes high-quality studies that explore the molecular mechanisms underlying cancer development, progression, and treatment. MCR serves as a platform for scientists and clinicians to share their findings, fostering advancements in cancer research and ultimately contributing to the development of novel therapeutic strategies.
Details
Details
Abbr.
Mol Cancer Res
Start
2002
End
Continuing
Frequency
Monthly
p-ISSN
1541-7786
e-ISSN
1557-3125
Country
United States
Language
English
Specialty
Cell Biology
Metrics
Metrics
h-index / Ranks: 1356
153
SJR / Ranks: 1637
1660
CiteScore / Ranks: 1269
10.60
JIF / Ranks: 1476
5.2
Recent Articles
1.
Huisman D, Chatterjee D, Svoboda R, Vieira H, Ireland A, Skupa S, et al.
Mol Cancer Res
. 2025 Mar;
PMID: 40063515
Small-cell lung carcinoma (SCLC) tumors are heterogeneous, with a subpopulation of cells primed for tumor initiation. Here, we show that Kinase Suppressor of Ras 2 (KSR2) promotes the self-renewal and...
2.
Lucchesi C, Mantrala S, Tran D, Batra N, Durve A, Suen C, et al.
Mol Cancer Res
. 2025 Mar;
PMID: 40052999
Multiple lines of correlative evidence support a role for ANGEL2, a novel cancer-relevant RNA-binding protein, in the modulation of chemoresistance and cancer patient survival. However, to date, no study has...
3.
Walker Z, Vaeth K, Baldwin A, Ohlstrom D, Reiman L, Dennis K, et al.
Mol Cancer Res
. 2025 Mar;
PMID: 40047825
Protein homeostasis is critical to the survival of multiple myeloma (MM) cells. While this is targeted with proteasome inhibitors, mRNA translation inhibition has not entered trials. Recent work illustrates broad...
4.
Insulin Resistance Increases TNBC Aggressiveness and Brain Metastasis via Adipocyte-derived Exosomes
Qiu Y, Chen A, Yu R, Llevenes P, Seen M, Ko N, et al.
Mol Cancer Res
. 2025 Mar;
PMID: 40047645
Patients with triple negative breast cancer (TNBC) and comorbid Type 2 Diabetes (T2D), characterized by insulin resistance of adipose tissue, have higher risk of metastasis and shorter survival. Adipocytes are...
5.
Ray P, Shukla S, Zhang Y, Donahue K, Nancarrow D, Kasturirangan S, et al.
Mol Cancer Res
. 2025 Feb;
PMID: 39976545
Cooperativity between mutant p53 and mutant KRAS, although recognized, is poorly understood. In pancreatic cancer, mutant p53 induces splicing factor hnRNPK causing isoform switch producing overexpression of GTPase activating protein...
6.
Kanayama K, Imai H, Hashizume R, Matsuda C, Usugi E, Hirokawa Y, et al.
Mol Cancer Res
. 2025 Feb;
PMID: 39969515
Chromosomal instability in gastric cancer cells is associated with the amplification of oncogenes that encode receptor tyrosine kinases (RTKs), such as HER2 and FGFR2; such gene amplification varies from cell...
7.
Alimova I, Wang D, DeSisto J, Danis E, Lakshmanachetty S, Prince E, et al.
Mol Cancer Res
. 2025 Feb;
PMID: 39960392
Atypical teratoid rhabdoid tumor (ATRT) is a highly aggressive pediatric brain tumor driven by the loss of SMARCB1, which results in epigenetic dysregulation of the genome. SMARCB1 loss affects lineage...
8.
Leung D, Liu K
Mol Cancer Res
. 2025 Feb;
PMID: 39945628
Approximately 97% of the human genome comprises non-coding sequences, with nearly half originating from transposable elements. Among these, retrotransposons represent a critical subclass that replicates via a "copy-and-paste" mechanism and...
9.
Chatterjee D, Svoboda R, Huisman D, Drapkin B, Vieira H, Rao C, et al.
Mol Cancer Res
. 2025 Feb;
PMID: 39927878
Small-cell lung cancer (SCLC) has a dismal five-year survival rate of less than 7%, with limited advances in first line treatment over the past four decades. Tumor-initiating cells (TICs) contribute...
10.
Wang W, Chaudhary R, Szpendyk J, El Khalki L, Yousafzai N, Chan R, et al.
Mol Cancer Res
. 2025 Feb;
PMID: 39918417
Triple-negative breast cancer (TNBC) presents significant clinical challenges due to its limited treatment options and aggressive behavior, often associated with poor prognosis. This study focuses on Kindlin-2, an adaptor protein,...