The Journal of Biological Chemistry
Overview
The Journal of Biological Chemistry (JBC) is a renowned scientific journal that publishes cutting-edge research in the field of biochemistry. It covers a wide range of topics, including molecular biology, cell biology, genetics, and metabolism. JBC is highly regarded for its rigorous peer-review process and its commitment to publishing high-quality, original research articles that contribute to our understanding of biological processes at the molecular level.
Details
Details
Abbr.
J Biol Chem
Start
1905
End
Continuing
Frequency
Weekly, 1994-
p-ISSN
0021-9258
e-ISSN
1083-351X
Country
United States
Language
English
Specialty
Biochemistry
Metrics
Metrics
h-index / Ranks: 20
556
SJR / Ranks: 1476
1766
CiteScore / Ranks: 1714
9.20
JIF / Ranks: 1690
4.8
Recent Articles
1.
Hannan F, Kooblall K, Stevenson M, Elajnaf T, Liu F, Lines K, et al.
J Biol Chem
. 2025 Mar;
:108404.
PMID: 40086735
Germline gain-of-function mutations of the calcium-sensing receptor (CaSR) result in autosomal dominant hypocalcemia type 1 (ADH1), which may cause symptomatic hypocalcemia with low parathyroid hormone (PTH) concentrations. Negative allosteric CaSR...
2.
Liu D, Huo X, Zhang X, Zhang Z
J Biol Chem
. 2025 Mar;
:108403.
PMID: 40086734
Pathological stress can lead to failure in the translocation of mitochondrial proteins, resulting in accumulation of unimported proteins within the cytosol and upregulation of proteasome for their quality control. Malfunction...
3.
Zhao Z, Yamamoto N, Young J, Solis N, Fong A, Al-Seragi M, et al.
J Biol Chem
. 2025 Mar;
:108395.
PMID: 40081575
YidC, a prominent member of the Oxa1 superfamily, is essential for the biogenesis of the bacterial inner membrane, significantly influencing its protein composition and lipid organization. It interacts with the...
4.
Liem N, Spreen A, Silapetere A, Hegemann P
J Biol Chem
. 2025 Mar;
:108401.
PMID: 40081574
Rhodopsin phosphodiesterases (RhPDEs) were first discovered in the choanoflagellate Salpingoeca rosetta, but their physiological role remained unknown. Their light-dependent modulation was found to be low, limiting optogenetic application. However, recent...
5.
Rippe C, Bastrup J, Holmberg J, Kawka K, Martinez M, Albinsson S, et al.
J Biol Chem
. 2025 Mar;
:108400.
PMID: 40081573
Age is a critical determinant of arterial disease, including aneurysm formation. Here, to understand the impact of aging on the arterial transcriptome, we leveraged RNA-sequencing data to define transcripts that...
6.
Dickerhof N, Ashby L, Ford D, Dilly J, Anderson R, Payne R, et al.
J Biol Chem
. 2025 Mar;
:108402.
PMID: 40081572
When neutrophils ingest pathogens into phagosomes, they generate large amounts of the superoxide radical through the reduction of molecular oxygen. Superoxide is essential for effective antimicrobial defence, but the precise...
7.
Shao X, Volk L
J Biol Chem
. 2025 Mar;
:108397.
PMID: 40074086
The human memory-associated protein KIBRA regulates synaptic plasticity and trafficking of AMPA-type glutamate receptors, and is implicated in multiple neuropsychiatric and cognitive disorders. How KIBRA forms complexes with and regulates...
8.
Li B, Baniasadi H, Liang J, Phillips M, Michael A
J Biol Chem
. 2025 Mar;
:108390.
PMID: 40074085
The polyamine spermine is a flexible linear teraamine found in bacteria and eukaryotes, and in all known cases is synthesized from triamine spermidine by addition of an aminopropyl group acquired...
9.
Mitochondrial glutaredoxin Grx5 functions as a central hub for cellular iron-sulfur cluster assembly
Pandey A, Pain J, Singh P, Dancis A, Pain D
J Biol Chem
. 2025 Mar;
:108391.
PMID: 40074084
Iron-sulfur (FeS) protein biogenesis in eukaryotes is mediated by two different machineries - one in the mitochondria and another in the cytoplasm. Glutaredoxin 5 (Grx5) is a component of the...
10.
Atser M, Wenyonu C, Rowe E, Leung C, Cen H, Queathem E, et al.
J Biol Chem
. 2025 Mar;
:108398.
PMID: 40074083
Pyruvate dehydrogenase kinase (PDK) 1 is one of four isozymes that inhibit the oxidative decarboxylation of pyruvate to acetyl-CoA via pyruvate dehydrogenase. PDK activity is elevated in fasting or starvation...