Methods in Molecular Biology
Overview
Methods in Molecular Biology is a renowned scientific journal that focuses on cutting-edge techniques and methodologies used in molecular biology research. It covers a wide range of topics, including DNA sequencing, gene expression analysis, protein purification, and cell culture techniques. With its comprehensive and detailed articles, this journal serves as an invaluable resource for researchers and scientists in the field of molecular biology.
Details
Details
Abbr.
Methods Mol Biol
Start
1984
End
Continuing
Frequency
Irregular
p-ISSN
1064-3745
e-ISSN
1940-6029
Country
United States
Language
English
Specialty
Molecular Biology
Metrics
Metrics
h-index / Ranks: 720
200
SJR / Ranks: 10393
399
CiteScore / Ranks: 10041
2.30
Recent Articles
1.
Pratsinis H, Mavrogonatou E, Zervou S, Triantis T, Hiskia A, Kletsas D
Methods Mol Biol
. 2025 Mar;
2906:315-359.
PMID: 40082365
Selective targeting of senescent cells has been thus far considered a widespread preventive strategy, as well as a main or adjuvant therapy for age-associated diseases, fueling the research on the...
2.
Mytilinaiou E, Kitopoulou K, Palikaras K
Methods Mol Biol
. 2025 Mar;
2906:301-313.
PMID: 40082364
As global life expectancy continues to rise, the need to understand and mitigate the effects of aging on human physiology has become increasingly important. Aging is characterized by cellular and...
3.
Louka X, Gumeni S, Trougakos I
Methods Mol Biol
. 2025 Mar;
2906:281-299.
PMID: 40082363
Cellular senescence, a complex biological process characterized by irreversible cell cycle arrest, contributes significantly to the development and progression of aging and of age-related diseases. Studying cellular senescence in vivo...
4.
Pavlou G
Methods Mol Biol
. 2025 Mar;
2906:271-279.
PMID: 40082362
This chapter examines the vital role of the vascular system and the impact of vascular senescence on health. It highlights the importance of vascular integrity and how its aging contributes...
5.
Paschalaki K, Pericleous C
Methods Mol Biol
. 2025 Mar;
2906:255-270.
PMID: 40082361
Endothelium regulates vascular homeostasis maintaining a healthy cardiovascular system but also plays a key role in tumor development, progression, and metastasis. Endothelial senescence can be driven by aging, DNA damage,...
6.
Martic I, Feldmann D, Cavinato M
Methods Mol Biol
. 2025 Mar;
2906:243-254.
PMID: 40082360
Oncogene activation triggers oncogene-induced senescence (OIS), a tumor-suppression mechanism characterized by mitochondrial dysfunction and the secretion of various factors collectively known as the senescence-associated secretory phenotype (SASP). Recent evidence highlights...
7.
Glytsou C
Methods Mol Biol
. 2025 Mar;
2906:229-242.
PMID: 40082359
Mitochondria are multifunctional organelles that play a crucial role in numerous cellular processes, including oncogene-induced senescence. Recent studies have demonstrated that mitochondria undergo notable morphological and functional changes during senescence,...
8.
Thanos D, Saiti A, Giannopoulos-Dimitriou A, Kontouli-Pertesi N, Gorgoulis V, Anagnostopoulos A
Methods Mol Biol
. 2025 Mar;
2906:215-227.
PMID: 40082358
Lipofuscin, a yellow-brown complex mainly found in cellular waste, accumulates in cells as a byproduct of cellular degradation processes and is commonly associated with aging and oxidative stress. Lipofuscin's molecular...
9.
Foutadakis S, Soureas K, Roupakia E, Besta S, Avgeris M, Kolettas E
Methods Mol Biol
. 2025 Mar;
2906:189-213.
PMID: 40082357
Cellular senescence, a state of permanent cell cycle arrest, recapitulates the aging process at the cellular level. It can be triggered by intrinsic or extrinsic factors including telomere shortening (replicative...
10.
Dragona E, Gagos S
Methods Mol Biol
. 2025 Mar;
2906:177-188.
PMID: 40082356
Telomere strand-specific, two-replication-round, chromosome orientation fluorescence in situ hybridization (2R telomeric-CO-FISH) is a molecular cytogenetic protocol that allows simultaneous detection of genomic and telomeric sister chromatid exchanges along with telomeric...