Jayne S Danska
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Explore the profile of Jayne S Danska including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Rajakumar S, Papp E, Lee K, Grandal I, Merico D, Liu C, et al.
Sci Transl Med
. 2020 Sep;
12(561).
PMID: 32938796
Although most children survive B cell acute lymphoblastic leukemia (B-ALL), they frequently experience long-term, treatment-related health problems, including osteopenia and osteonecrosis. Because some children present with fractures at ALL diagnosis,...
12.
Dai H, Lan P, Zhao D, Abou-Daya K, Liu W, Chen W, et al.
Science
. 2020 May;
368(6495):1122-1127.
PMID: 32381589
Immunological memory specific to previously encountered antigens is a cardinal feature of adaptive lymphoid cells. However, it is unknown whether innate myeloid cells retain memory of prior antigenic stimulation and...
13.
Dobson S, Garcia-Prat L, Vanner R, Wintersinger J, Waanders E, Gu Z, et al.
Cancer Discov
. 2020 Feb;
10(4):568-587.
PMID: 32086311
Disease recurrence causes significant mortality in B-progenitor acute lymphoblastic leukemia (B-ALL). Genomic analysis of matched diagnosis and relapse samples shows relapse often arising from minor diagnosis subclones. However, why therapy...
14.
Galkin O, McLeod J, Kennedy J, Jin L, Mbong N, Wong M, et al.
Haematologica
. 2020 Feb;
106(1):279-283.
PMID: 32054659
No abstract available.
15.
Paun A, Yau C, Meshkibaf S, Daigneault M, Marandi L, Mortin-Toth S, et al.
Sci Immunol
. 2019 Feb;
4(32).
PMID: 30709843
Microbiome sequence analyses have suggested that changes in gut bacterial composition are associated with autoimmune disease in humans and animal models. However, little is known of the mechanisms through which...
16.
Verdu E, Danska J
Nat Immunol
. 2018 Jun;
19(7):685-695.
PMID: 29925984
Risk factors for most autoimmune diseases are multifactorial genetic variants modified by environmental risk factors. Type 1 diabetes and celiac disease share high-risk HLA haplotypes, and the prevalence of both...
17.
Israelian N, Danska J
Adv Exp Med Biol
. 2017 Dec;
1043:113-140.
PMID: 29224093
The relationships between dietary compounds, derivative metabolites, and host metabolism and immunity are controlled by diverse molecular mechanisms. Essential contributions to these dynamics come from the community of microbes (the...
18.
Dai H, Friday A, Abou-Daya K, Williams A, Mortin-Toth S, Nicotra M, et al.
Sci Immunol
. 2017 Aug;
2(12).
PMID: 28783664
Mice devoid of T, B, and natural killer (NK) cells distinguish between self and allogeneic nonself despite the absence of an adaptive immune system. When challenged with an allograft, they...
19.
Chen J, Zhong M, Guo H, Davidson D, Mishel S, Lu Y, et al.
Nature
. 2017 Apr;
544(7651):493-497.
PMID: 28424516
Cancer cells elude anti-tumour immunity through multiple mechanisms, including upregulated expression of ligands for inhibitory immune checkpoint receptors. Phagocytosis by macrophages plays a critical role in cancer control. Therapeutic blockade...
20.
Paun A, Yau C, Danska J
J Immunol
. 2017 Jan;
198(2):590-595.
PMID: 28069754
Type 1 diabetes (T1D) is characterized by the autoimmune destruction of pancreatic β cells. The rapid rise in T1D incidence during the past 50 y suggests environmental factors contribute to...