Cancer Discovery
Overview
Cancer Discovery is a prestigious scientific journal that publishes cutting-edge research in the field of cancer biology and therapeutics. It provides a platform for scientists and clinicians to share groundbreaking discoveries, novel treatment strategies, and emerging technologies that advance our understanding and management of cancer. With its rigorous peer-review process and multidisciplinary approach, Cancer Discovery is a vital resource for researchers, oncologists, and healthcare professionals seeking to stay at the forefront of cancer research.
Details
Details
Abbr.
Cancer Discov
Start
2011
End
Continuing
Frequency
Monthly
p-ISSN
2159-8274
e-ISSN
2159-8290
Country
United States
Language
English
Specialty
Oncology
Metrics
Metrics
h-index / Ranks: 477
229
SJR / Ranks: 129
7533
CiteScore / Ranks: 287
21.90
JIF / Ranks: 90
28.2
Recent Articles
1.
Garcia G, Orellana T, Gorecki G, Frisbie L, Baruwal R, Suresh S, et al.
Cancer Discov
. 2025 Mar;
PMID: 40084985
The fundamental steps in high-grade serous ovarian cancer (HGSOC) initiation are unclear presenting critical barriers in prevention and early detection of this deadly disease. Current models propose that fallopian tube...
2.
Li Y, Kandyba E, Halliwill K, Delrosario R, Tran Q, Bayani N, et al.
Cancer Discov
. 2025 Mar;
PMID: 40073432
Historical studies performed nearly a century ago using mouse skin models identified two key steps in cancer evolution: initiation, a likely mutational event, and promotion, driven by inflammation and cell...
3.
Bleve A, Incerti M, Consonni F, Garlatti V, Ballerini G, Pandolfo C, et al.
Cancer Discov
. 2025 Mar;
PMID: 40066819
Despite well-documented metabolic and hematopoietic alterations during tumor development, the mechanisms underlying this crucial immunometabolic intersection remain elusive. Of particular interest is the connection between lipid metabolism and the retinoic-acid-related...
4.
Lv W, Zeng Y, Li C, Liang Y, Tao H, Zhu Y, et al.
Cancer Discov
. 2025 Mar;
PMID: 40062518
Extrachromosomal DNA (ecDNA) presents a promising target for cancer therapy; however, its spatial-temporal diversity and influence on tumor evolution and the immune microenvironment remain largely unclear. We apply computational methods...
5.
Orlen M, Vostrejs W, Sor R, McDevitt J, Kemp S, Kim I, et al.
Cancer Discov
. 2025 Mar;
PMID: 40057911
Activating mutations in KRAS drive tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), promoting tumor cell proliferation and contributing to an immunosuppressive tumor microenvironment (TME) rendering PDAC tumors insensitive to immunotherapy. RAS(ON)...
6.
Ben-Shmuel A, Gruper Y, Halperin C, Levi-Galibov O, Rosenberg-Fogler H, Barki D, et al.
Cancer Discov
. 2025 Mar;
PMID: 40052789
Cancer-associated fibroblasts (CAFs) are abundant components of the breast tumor microenvironment and major contributors to immune-modulation. CAFs regulate the activity of many immune cells including T-cells, macrophages and dendritic cells,...
7.
Eccles R, Carreno G, de la Rica L, Balmer G, Scott D
Cancer Discov
. 2025 Mar;
:OF1-OF5.
PMID: 40042494
Here, we discuss the seven new challenges set by Cancer Grand Challenges that are currently open for creative applications. We invite the research community to assemble global, interdisciplinary teams to...
8.
Chen C, Cai Y, Hu W, Tan K, Lu Z, Zhu X, et al.
Cancer Discov
. 2025 Mar;
PMID: 40029140
Colorectal cancer (CRC) is a heterogeneous disease that develops through a stepwise accumulation, yet the underlying mechanisms at single-cell resolution remain unclear. Here, we profiled 751,531 single-cell transcriptomes, spatial transcriptomics,...
9.
Wiegering A, Uthe F, Jamieson T, Ruoss Y, Huttenrauch M, Kuspert M, et al.
Cancer Discov
. 2025 Mar;
15(3):656.
PMID: 40025952
No abstract available.
10.
Venneti S, Kawakibi A, Ji S, Waszak S, Sweha S, Mota M, et al.
Cancer Discov
. 2025 Mar;
15(3):657.
PMID: 40025951
No abstract available.