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Science Translational Medicine

Science Translational Medicine is a prestigious peer-reviewed journal that bridges the gap between scientific research and clinical application. It publishes cutting-edge studies that translate laboratory discoveries into practical solutions for diagnosing, treating, and preventing human diseases. With a multidisciplinary approach, this journal serves as a vital resource for scientists, clinicians, and policymakers seeking to advance medical knowledge and improve patient care.

Details
Abbr. Sci Transl Med
Start 2009
End Continuing
Frequency Monthly
p-ISSN 1946-6234
e-ISSN 1946-6242
Country United States
Language English
Metrics
h-index / Ranks: 250 284
SJR / Ranks: 163 6510
CiteScore / Ranks: 213 24.80
JIF / Ranks: 187 17.1
Recent Articles
1.
Liu N, Jiang Y, Xiu Y, Tortelote G, Xia W, Wang Y, et al.
Sci Transl Med . 2025 Mar; 17(789):eadn2635. PMID: 40073156
Traumatic brain injury (TBI) rapidly triggers proinflammatory activation of microglia, contributing to secondary brain damage post-TBI. Although the governing role of energy metabolism in shaping the inflammatory phenotype and function...
2.
Foster D, Guo J, Meany E, Berry C, Fallah M, Korah M, et al.
Sci Transl Med . 2025 Mar; 17(789):eadp9957. PMID: 40073155
Postoperative abdominal adhesions are the leading cause of bowel obstruction and a cause of chronic pain and infertility. Adhesion formation occurs after 50 to 90% of abdominal operations and has...
3.
Hu X, Kang X, Zhao F, Cui Y, Fu Y, Yang X, et al.
Sci Transl Med . 2025 Mar; 17(789):eadp2124. PMID: 40073154
The benefit of hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer remains controversial, hindering the development of rational combination therapies based on hyperthermia (HT). This study reports the preliminary results of...
4.
Gu Y, Singh S, Alqarihi A, Alkhazraji S, Gebremariam T, Youssef E, et al.
Sci Transl Med . 2025 Mar; 17(789):eads7369. PMID: 40073153
Mucormycosis is a fungal infection caused by Mucorales fungi that cause severe disease and fatality, especially in immunocompromised individuals. Although vaccines and immunotherapeutics have been successful in combating viral and...
5.
Wang H, Taher H, Kreklywich C, Schmidt K, Scheef E, Barfield R, et al.
Sci Transl Med . 2025 Mar; 17(789):eadm8961. PMID: 40073152
Congenital cytomegalovirus (cCMV) is the leading infectious cause of neonatal neurological impairment worldwide, but the viral factors enabling vertical spread across the placenta remain undetermined. The pentameric complex (PC), composed...
6.
Nangle L, Xu Z, Siefker D, Burkart C, Chong Y, Zhai L, et al.
Sci Transl Med . 2025 Mar; 17(789):eadp4754. PMID: 40073151
Interstitial lung disease (ILD) consists of a group of immune-mediated disorders that can cause inflammation and progressive fibrosis of the lungs, representing an area of unmet medical need given the...
7.
Mumme M, Wixmerten A, Ivkovic A, Peretti G, Yilmaz T, Reppenhagen S, et al.
Sci Transl Med . 2025 Mar; 17(788):eads0848. PMID: 40043142
Cartilage lesions do not heal spontaneously and predispose to osteoarthritis. Functional cartilage tissues, engineered using autologous chondrocytes, have a therapeutic advantage over conventional cellular therapies in preclinical studies. Here, we...
8.
Olaloye O, Gu W, Gehlhaar A, Sabuwala B, Eke C, Li Y, et al.
Sci Transl Med . 2025 Mar; 17(788):eadr0942. PMID: 40043141
Extremely premature infants (EPIs) who are born before 30 weeks of gestation are susceptible to infection; however, the trajectory of their peripheral immunity is poorly understood. Here, we undertook longitudinal...
9.
Sun S, Qian S, Wang R, Zhao M, Li R, Gu W, et al.
Sci Transl Med . 2025 Mar; 17(788):eado0020. PMID: 40043140
Radiotherapy (RT) has been the standard-of-care treatment for patients with glioblastoma (GBM); however, the clinical effectiveness is hindered by therapeutic resistance. Here, we demonstrated that the tumor immune microenvironment (TIME)...
10.
Rubio A, Baharani V, Dadonaite B, Parada M, Abernathy M, Wang Z, et al.
Sci Transl Med . 2025 Mar; 17(788):eadq5720. PMID: 40043139
The ongoing emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that reduce the effectiveness of antibody therapeutics necessitates development of next-generation antibody modalities that are...