Advances in Experimental Medicine and Biology
Overview
Advances in Experimental Medicine and Biology is a renowned interdisciplinary journal that publishes cutting-edge research in the field of experimental medicine and biology. It covers a wide range of topics, including molecular biology, genetics, immunology, neuroscience, and pharmacology. With a focus on advancing scientific knowledge and understanding, this journal serves as a valuable resource for researchers, scientists, and healthcare professionals seeking to stay updated on the latest advancements in these fields.
Details
Details
Abbr.
Adv Exp Med Biol
Start
1967
End
Continuing
Frequency
Irregular
p-ISSN
0065-2598
e-ISSN
2214-8019
Country
United States
Language
English
Specialties
General Medicine
Biology
Biology
Metrics
Metrics
h-index / Ranks: 1321
155
SJR / Ranks: 12781
244
CiteScore / Ranks: 3626
6.20
Recent Articles
1.
Santana-Goncalves M, De Santis P, Malmegrim K, Oliveira M
Adv Exp Med Biol
. 2025 Mar;
1471:301-323.
PMID: 40067593
Over the last three decades, autologous hematopoietic stem cell transplantation (AHSCT) has emerged as a significant therapeutic strategy for patients with various refractory autoimmune diseases. Globally, more than 3000 AHSCT...
2.
Lins M, Dos Santos Reis M
Adv Exp Med Biol
. 2025 Mar;
1471:285-299.
PMID: 40067592
The age-related thymic involution has intrigued scientists since its first observations. This phenomenon is well-conserved across different species, but the reason why it exists is not clear since the thymus...
3.
Tanaka P, Monteiro C, Duarte M, Oliveira E, Monteleone-Cassiano A, Mascarenhas R, et al.
Adv Exp Med Biol
. 2025 Mar;
1471:269-283.
PMID: 40067591
Although mutations in the AIRE gene in patients with autoimmune polyendocrine syndrome type 1 (APS-1) syndrome are associated with the onset of this autoimmune disease, much of what is known...
4.
Passos G, Genari A, Assis A, Monteleone-Cassiano A, Donadi E, Oliveira E, et al.
Adv Exp Med Biol
. 2025 Mar;
1471:247-268.
PMID: 40067590
The thymus, a complex organ formed by different cell types that establish close interaction, serves a unique function of significant interest. The role played by the thymic stroma is not...
5.
Wolff A, Oftedal B
Adv Exp Med Biol
. 2025 Mar;
1471:223-246.
PMID: 40067589
Autoimmune diseases were first recognized by Mackay and Macfarlane Burnet in 1962 (Burnet and Mackay 1962). It is defined as the failure of an organism to tolerate its own cells...
6.
Giraud M, Peterson P
Adv Exp Med Biol
. 2025 Mar;
1471:199-221.
PMID: 40067588
It has been more than 20 years since the AIRE gene was discovered. The mutations in the AIRE gene cause a rare and life-threatening autoimmune disease with severe manifestations against...
7.
Irla M
Adv Exp Med Biol
. 2025 Mar;
1471:177-197.
PMID: 40067587
The thymus ensures the generation of a self-tolerant T-cell repertoire capable of recognizing foreign antigens. The selection of the T-cell repertoire is dictated by the thymic microenvironment. Among stromal cells,...
8.
Mendes-da-Cruz D, Lemos J, Belorio E, Savino W
Adv Exp Med Biol
. 2025 Mar;
1471:139-175.
PMID: 40067586
During the development of T cells in the thymus, differentiating thymocytes move through specific thymic compartments and interact with the cortical and medullary microenvironments of the thymic lobules. This migration...
9.
Golzari-Sorkheh M, Yoganathan K, Chen E, Singh J, Zuniga-Pflucker J
Adv Exp Med Biol
. 2025 Mar;
1471:81-137.
PMID: 40067585
T cell development occurs in the thymus in both mice and humans. Upon entry into the thymus, bone marrow-derived blood-borne progenitors receive instructive signals, including Notch signaling, to eliminate their...
10.
Matsumoto M, Sobral F, Cardoso J, Oya T, Tsuneyama K, Matsumoto M, et al.
Adv Exp Med Biol
. 2025 Mar;
1471:51-79.
PMID: 40067584
The thymus is an essential component of the immune system responsible for producing T cells. It is anatomically divided into two main regions: the outer cortex and the inner medulla....