Steven Mortin-Toth
Overview
Explore the profile of Steven Mortin-Toth including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
1175
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0
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Recent Articles
1.
Dai H, Lan P, Zhao D, Abou-Daya K, Liu W, Chen W, et al.
Science
. 2020 May;
368(6495):1122-1127.
PMID: 32381589
Immunological memory specific to previously encountered antigens is a cardinal feature of adaptive lymphoid cells. However, it is unknown whether innate myeloid cells retain memory of prior antigenic stimulation and...
2.
Paun A, Yau C, Meshkibaf S, Daigneault M, Marandi L, Mortin-Toth S, et al.
Sci Immunol
. 2019 Feb;
4(32).
PMID: 30709843
Microbiome sequence analyses have suggested that changes in gut bacterial composition are associated with autoimmune disease in humans and animal models. However, little is known of the mechanisms through which...
3.
Dai H, Friday A, Abou-Daya K, Williams A, Mortin-Toth S, Nicotra M, et al.
Sci Immunol
. 2017 Aug;
2(12).
PMID: 28783664
Mice devoid of T, B, and natural killer (NK) cells distinguish between self and allogeneic nonself despite the absence of an adaptive immune system. When challenged with an allograft, they...
4.
Motta V, Markle J, Gulban O, Mortin-Toth S, Liao K, Mogridge J, et al.
J Immunol
. 2015 May;
194(12):5663-73.
PMID: 25964492
Type 1 diabetes in the NOD mouse model has been linked to >30 insulin-dependent diabetes (Idd) susceptibility loci. Idd4 on chromosome 11 consists of two subloci, Idd4.1 and Idd4.2. Using...
5.
Wong A, Mortin-Toth S, Sung M, Canty A, Gulban O, Greaves D, et al.
J Immunol
. 2014 Oct;
193(10):4833-44.
PMID: 25305319
The signal regulatory protein (SIRP) locus encodes a family of paired receptors that mediate both activating and inhibitory signals and is associated with type 1 diabetes (T1D) risk. The NOD...
6.
Markle J, Frank D, Mortin-Toth S, Robertson C, Feazel L, Rolle-Kampczyk U, et al.
Science
. 2013 Jan;
339(6123):1084-8.
PMID: 23328391
Microbial exposures and sex hormones exert potent effects on autoimmune diseases, many of which are more prevalent in women. We demonstrate that early-life microbial exposures determine sex hormone levels and...
7.
Chiu P, Ivakine E, Mortin-Toth S, Danska J
Cancer Res
. 2002 Oct;
62(20):5828-34.
PMID: 12384545
Transformed lymphocytes exhibit aberrant growth potential resulting from enhanced proliferation and resistance to apoptotic stimuli. These mechanisms also influence the development of autoimmune disease, where dysregulated lymphocyte homeostasis has been...