The Journal of Experimental Medicine
Overview
The Journal of Experimental Medicine is a prestigious scientific journal that publishes groundbreaking research in the field of biomedical sciences. It focuses on studies that explore the mechanisms of disease, novel therapeutic approaches, and the fundamental understanding of human biology. With rigorous peer-review and a global readership, this journal serves as a platform for disseminating cutting-edge discoveries and advancing medical knowledge.
Details
Details
Abbr.
J Exp Med
Start
1896
End
Continuing
Frequency
Monthly, 2017-
p-ISSN
0022-1007
e-ISSN
1540-9538
Country
United States
Language
English
Specialties
General Medicine
Allergy & Immunology
Allergy & Immunology
Metrics
Metrics
h-index / Ranks: 36
490
SJR / Ranks: 151
6838
CiteScore / Ranks: 225
24.10
JIF / Ranks: 219
15.3
Recent Articles
1.
Churchill M, Pandeya A, Bauer R, Christopher T, Krug S, Honodel R, et al.
J Exp Med
. 2025 Mar;
222(6).
PMID: 40079814
To distinguish pathogens from commensals, the intestinal epithelium employs cytosolic innate immune sensors. Activation of the NAIP-NLRC4 inflammasome initiates extrusion of infected intestinal epithelial cells (IEC) upon cytosolic bacterial sensing....
2.
Pestal K, Slayden L, Barton G
J Exp Med
. 2025 Mar;
222(5).
PMID: 40072341
Tissue-resident macrophages adopt distinct gene expression profiles and exhibit functional specialization based on their tissue of residence. Recent studies have begun to define the signals and transcription factors that induce...
3.
Jang G, Park R, Esteva E, Hsu P, Feng J, Upadhaya S, et al.
J Exp Med
. 2025 Mar;
222(6).
PMID: 40072317
Leukemia-driving mutations are thought to arise in hematopoietic stem cells (HSC), yet the natural history of their spread is poorly understood. We genetically induced mutations within endogenous murine HSC and...
4.
Murphy B, Miyamoto T, Manning B, Mirji G, Ugolini A, Kannan T, et al.
J Exp Med
. 2025 Mar;
222(4).
PMID: 40067151
No abstract available.
5.
Broomfield B, Tan C, Qin R, Abberger H, Duckworth B, Alvarado C, et al.
J Exp Med
. 2025 Mar;
222(5).
PMID: 40062995
Developing vaccines that promote CD8+ T cell memory is a challenge for infectious disease and cancer immunotherapy. TCF-1+ stem cell-like memory CD8+ T (TSCM) cells are important determinants of long-lived...
6.
Peckham H, Radziszewska A, Sikora J, de Gruijter N, Restuadi R, Kartawinata M, et al.
J Exp Med
. 2025 Mar;
222(4).
PMID: 40049222
Sex differences in immunity are well-documented, though mechanisms underpinning these differences remain ill-defined. Here, in a human-only ex vivo study, we demonstrate that postpubertal cisgender females have higher levels of...
7.
Qin W, Duan Y, Hu Z, Hou Y, Wen T, Ouyang Y, et al.
J Exp Med
. 2025 Mar;
222(5).
PMID: 40048154
Hypoxia induces immunosuppressive phenotypes in tumor cells even in the presence of cytosolic DNA accumulation. The mechanisms by which tumor cells suppress hypoxia-induced cGAS-STING activation for immune evasion remain largely...
8.
Duthoo E, Beyls E, Backers L, Gudjonsson T, Huang P, Jonckheere L, et al.
J Exp Med
. 2025 Mar;
222(5).
PMID: 40029331
Ataxia telangiectasia and Rad3-related (ATR) kinase and its interacting protein ATRIP orchestrate the replication stress response. Homozygous splice variants in the ATRIP gene, resulting in ATRIP deficiency, were identified in...
9.
Simchoni N, Koide S, Likhite M, Kuchitsu Y, Kadirvel S, Law C, et al.
J Exp Med
. 2025 Feb;
222(4).
PMID: 40014299
COPA syndrome, an autosomal-dominant inborn error of immunity, is nonpenetrant in ∼20% of individuals, with no known mediators of protection. Recent studies implicate STING in the pathogenesis of COPA syndrome....
10.
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, et al.
J Exp Med
. 2025 Feb;
222(4).
PMID: 40009071
No abstract available.