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Janet G M Markle

Explore the profile of Janet G M Markle including associated specialties, affiliations and a list of published articles. Areas
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Citations 1081
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Recent Articles
1.
Motta V, Markle J, Gulban O, Mortin-Toth S, Liao K, Mogridge J, et al.
J Immunol . 2015 May; 194(12):5663-73. PMID: 25964492
Type 1 diabetes in the NOD mouse model has been linked to >30 insulin-dependent diabetes (Idd) susceptibility loci. Idd4 on chromosome 11 consists of two subloci, Idd4.1 and Idd4.2. Using...
2.
Markle J, Frank D, Adeli K, von Bergen M, Danska J
Gut Microbes . 2014 Jul; 5(4):485-93. PMID: 25007153
Despite growing evidence for a causal role of environmental factors in autoimmune diseases including the rise in disease frequencies over the past several decades we lack an understanding of how...
3.
Markle J, Mortin-Toth S, Wong A, Geng L, Hayday A, Danska J
J Immunol . 2013 Apr; 190(11):5392-401. PMID: 23626013
γδ T cells, a lineage of innate-like lymphocytes, are distinguished from conventional αβ T cells in their Ag recognition, cell activation requirements, and effector functions. γδ T cells have been...
4.
Markle J, Frank D, Mortin-Toth S, Robertson C, Feazel L, Rolle-Kampczyk U, et al.
Science . 2013 Jan; 339(6123):1084-8. PMID: 23328391
Microbial exposures and sex hormones exert potent effects on autoimmune diseases, many of which are more prevalent in women. We demonstrate that early-life microbial exposures determine sex hormone levels and...