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Xavier Hernandez-Alias

Explore the profile of Xavier Hernandez-Alias including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 134
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Recent Articles
1.
Benisty H, Hernandez-Alias X, Weber M, Anglada-Girotto M, Mantica F, Radusky L, et al.
Cell Syst . 2023 Mar; 14(4):312-323.e3. PMID: 36889307
Codon usage influences gene expression distinctly depending on the cell context. Yet, the importance of codon bias in the simultaneous turnover of specific groups of protein-coding genes remains to be...
2.
Hernandez-Alias X, Benisty H, Radusky L, Serrano L, Schaefer M
Genome Biol . 2023 Feb; 24(1):34. PMID: 36829202
Background: Codon usage and nucleotide composition of coding sequences have profound effects on protein expression. However, while it is recognized that different tissues have distinct tRNA profiles and codon usages...
3.
Hernandez-Alias X, Katanski C, Zhang W, Assari M, Watkins C, Schaefer M, et al.
Nucleic Acids Res . 2022 Dec; 51(3):e17. PMID: 36537222
Transfer RNA (tRNA) utilizes multiple properties of abundance, modification, and aminoacylation in translational regulation. These properties were typically studied one-by-one; however, recent advance in high throughput tRNA sequencing enables their...
4.
Ghose R, Aranguren-Ibanez A, Arecco N, Balboa D, Bataller M, Beltran S, et al.
F1000Res . 2021 Nov; 9:1336. PMID: 34745570
The COVID-19 pandemic has posed and is continuously posing enormous societal and health challenges worldwide. The research community has mobilized to develop novel projects to find a cure or a...
5.
Hernandez-Alias X, Benisty H, Schaefer M, Serrano L
Mol Syst Biol . 2021 Mar; 17(3):e10097. PMID: 33759329
No abstract available.
6.
Hernandez-Alias X, Benisty H, Schaefer M, Serrano L
Cell Rep . 2021 Mar; 34(11):108872. PMID: 33730572
Viruses need to hijack the translational machinery of the host cell for a productive infection to happen. However, given the dynamic landscape of tRNA pools among tissues, it is unclear...
7.
Head S, Hernandez-Alias X, Yang J, Ciampi L, Beltran-Sastre V, Torres-Mendez A, et al.
PLoS Biol . 2021 Feb; 19(2):e3001138. PMID: 33621242
RNA splicing is widely dysregulated in cancer, frequently due to altered expression or activity of splicing factors (SFs). Microexons are extremely small exons (3-27 nucleotides long) that are highly evolutionarily...
8.
Tarrago-Celada J, Foguet C, Tarrado-Castellarnau M, Marin S, Hernandez-Alias X, Perarnau J, et al.
Cancers (Basel) . 2021 Jan; 13(3). PMID: 33498690
With most cancer-related deaths resulting from metastasis, the development of new therapeutic approaches against metastatic colorectal cancer (mCRC) is essential to increasing patient survival. The metabolic adaptations that support mCRC...
9.
Blanco J, Hernandez-Alias X, Cianferoni D, Serrano L
PLoS Comput Biol . 2020 Dec; 16(12):e1008450. PMID: 33284795
The coronavirus disease COVID-19 constitutes the most severe pandemic of the last decades having caused more than 1 million deaths worldwide. The SARS-CoV-2 virus recognizes the angiotensin converting enzyme 2...
10.
Benisty H, Weber M, Hernandez-Alias X, Schaefer M, Serrano L
Proc Natl Acad Sci U S A . 2020 Nov; 117(48):30848-30856. PMID: 33199641
It is well known that in cancer gene families some members are more frequently mutated in tumor samples than their family counterparts. A paradigmatic case of this phenomenon is KRAS...