Cell Systems
Overview
Cell Systems is a peer-reviewed scientific journal that focuses on systems biology and systems medicine. It publishes cutting-edge research articles, reviews, and perspectives that explore the complex interactions within biological systems at various scales, from molecules to cells to organisms. The journal aims to advance our understanding of cellular processes, disease mechanisms, and therapeutic interventions through interdisciplinary approaches and innovative methodologies.
Details
Details
Abbr.
Cell Syst
Publisher
Cell Press
Start
2015
End
Continuing
Frequency
Monthly, 2016-
p-ISSN
2405-4712
e-ISSN
2405-4720
Country
United States
Language
English
Specialties
Biology
Cell Biology
Molecular Biology
Cell Biology
Molecular Biology
Metrics
Metrics
h-index / Ranks: 3865
87
SJR / Ranks: 275
4872
CiteScore / Ranks: 427
18.30
JIF / Ranks: 519
9.3
Recent Articles
1.
Wang N, Adewumi H, Lende-Dorn B, Beitz A, OShea T, Galloway K
Cell Syst
. 2025 Mar;
:101206.
PMID: 40086435
Direct conversion generates patient-specific, disease-relevant cell types, such as neurons, that are rare, limited, or difficult to isolate from common and easily accessible cells, such as skin cells. However, low...
2.
Wang N, Lende-Dorn B, Beitz A, Han P, Adewumi H, OShea T, et al.
Cell Syst
. 2025 Mar;
:101205.
PMID: 40086434
The sparse and stochastic nature of conversion has obscured our understanding of how transcription factors (TFs) drive cells to new identities. To overcome this limit, we develop a tailored, high-efficiency...
3.
Thomas N, Belanger D, Xu C, Lee H, Hirano K, Iwai K, et al.
Cell Syst
. 2025 Mar;
:101236.
PMID: 40081373
Optimizing enzymes to function in novel chemical environments is a central goal of synthetic biology, but optimization is often hindered by a rugged fitness landscape and costly experiments. In this...
4.
Benman W, Iyengar P, Mumford T, Huang Z, Kapoor M, Liu G, et al.
Cell Syst
. 2025 Mar;
:101234.
PMID: 40081372
Temperature is an important biological stimulus, yet there is a lack of approaches to modulate the temperature of biological samples in a dynamic and high-throughput manner. The thermoPlate is a...
5.
Yuan Y, Huang C, Singh N, Xun G, Zhao H
Cell Syst
. 2025 Mar;
:101237.
PMID: 40073866
Natural products (NPs) from bacteria, fungi, and plants are a vital source of drug leads, with Streptomyces species being particularly significant due to their capability of producing diverse bioactive compounds....
6.
Mei Y, Gosztyla M, Tan X, Dozier L, Wilkinson B, McKetney J, et al.
Cell Syst
. 2025 Mar;
:101204.
PMID: 40054464
The molecular composition of the excitatory synapse is incompletely defined due to its dynamic nature across developmental stages and neuronal populations. To address this gap, we apply proteomic mass spectrometry...
7.
Mahajan S, Davila-Hernandez F, Ruffolo J, Gray J
Cell Syst
. 2025 Mar;
:101201.
PMID: 40043698
In proteins, the optimal residue at any position is determined by its structural, evolutionary, and functional contexts-much like how a word may be inferred from its context in language. We...
8.
Suh K, Thornton R, Nguyen L, Farahani P, Cohen D, Toettcher J
Cell Syst
. 2025 Mar;
:101203.
PMID: 40037348
Receptor tyrosine kinases (RTKs) play key roles in coordinating cell movement at both single-cell and tissue scales. The recent development of optogenetic tools for controlling RTKs and their downstream signaling...
9.
Su W, Xia Y
Cell Syst
. 2025 Mar;
:101202.
PMID: 40023148
Regions on a host protein that interact with virus proteins (exogenous interfaces) frequently overlap with those that interact with other host proteins (endogenous interfaces), resulting in competition between hosts and...
10.
Moffitt J, Li M, Nie Q, Kanemaru K, Teichmann S, Dar D, et al.
Cell Syst
. 2025 Feb;
16(2):101200.
PMID: 39978311
No abstract available.