Plos Computational Biology
Overview
PLoS Computational Biology is a peer-reviewed open-access journal that publishes research articles, reviews, and perspectives at the intersection of computational and biological sciences. It covers a wide range of topics including genomics, systems biology, bioinformatics, and computational modeling, fostering the advancement of computational approaches in understanding biological processes.
Details
Details
Abbr.
PLoS Comput Biol
Start
2005
End
Continuing
Frequency
Monthly
p-ISSN
1553-734X
e-ISSN
1553-7358
Country
United States
Language
English
Specialty
Biology
Metrics
Metrics
h-index / Ranks: 559
217
SJR / Ranks: 1653
1652
CiteScore / Ranks: 2824
7.10
JIF / Ranks: 2027
4.3
Recent Articles
1.
Haiman Z, Key A, DAlessandro A, Palsson B
PLoS Comput Biol
. 2025 Mar;
21(3):e1012109.
PMID: 40072998
Advancements with cost-effective, high-throughput omics technologies have had a transformative effect on both fundamental and translational research in the medical sciences. These advancements have facilitated a departure from the traditional...
2.
Gray C, Chitnavis S, Buja T, Duffy C
PLoS Comput Biol
. 2025 Mar;
21(3):e1012845.
PMID: 40067883
Oxygenic photosynthesis is responsible for nearly all biomass production on Earth, and may have been a prerequisite for establishing a complex biosphere rich in multicellular life. Life on Earth has...
3.
Han X, Song K
PLoS Comput Biol
. 2025 Mar;
21(3):e1012858.
PMID: 40067818
In microbiome research, data sparsity represents a prevalent and formidable challenge. Sparse data not only compromises the accuracy of statistical analyses but also conceals critical biological relationships, thereby undermining the...
4.
Vayena E, Fuchs L, Peyhani H, Lagoda K, Nguyen B, Hardt W, et al.
PLoS Comput Biol
. 2025 Mar;
21(3):e1012869.
PMID: 40067815
Nontyphoidal Salmonella strains (NTS) are among the most common foodborne enteropathogens and constitute a major cause of global morbidity and mortality, imposing a substantial burden on global health. The increasing...
5.
Sigalas E, Libedinsky C
PLoS Comput Biol
. 2025 Mar;
21(3):e1012867.
PMID: 40067809
The functional properties of a network depend on its connectivity, which includes the strength of its inputs and the strength of the connections between its units, or recurrent connectivity. Because...
6.
Burgers E, Sharma R, Eugenio C, Heldring M, Wijaya L, van de Water B, et al.
PLoS Comput Biol
. 2025 Mar;
21(3):e1012844.
PMID: 40063860
Cells exposed to toxicants, such as drugs, activate a wide variety of stress pathways, often simultaneously. Two important pathways that can influence cell fate and consequently adverse reactions are the...
7.
Oprysk L, Vazquez M, Shinbrot T
PLoS Comput Biol
. 2025 Mar;
21(3):e1012769.
PMID: 40063623
Experiments demonstrate that individual cells that wander stochastically can migrate persistently as a cluster. We show by simulating cells and their interactions that collective migration by omnidirectional cells is a...
8.
Wang Z, Yang Y, Huang Z, Zhao W, Su K, Zhu H, et al.
PLoS Comput Biol
. 2025 Mar;
21(3):e1012870.
PMID: 40053566
Understanding the large-scale information processing that underlies complex human cognition is the central goal of cognitive neuroscience. While emerging activity flow models demonstrate that cognitive task information is transferred by...
9.
Alteriis G, Sherwood O, Ciaramella A, Leech R, Cabral J, Turkheimer F, et al.
PLoS Comput Biol
. 2025 Mar;
21(3):e1012795.
PMID: 40053563
A crucial challenge in neuroscience involves characterising brain dynamics from high-dimensional brain recordings. Dynamic Functional Connectivity (dFC) is an analysis paradigm that aims to address this challenge. dFC consists of...
10.
Heng J, Woodford M, Polania R
PLoS Comput Biol
. 2025 Mar;
21(3):e1012790.
PMID: 40053561
The ability to rapidly estimate non-symbolic numerical quantities is a well-conserved sense across species with clear evolutionary advantages. However, despite its importance, this sense is surprisingly imprecise and biased, and...