Luis Serrano
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Explore the profile of Luis Serrano including associated specialties, affiliations and a list of published articles.
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297
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11856
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Recent Articles
1.
Delgado J, Reche R, Cianferoni D, Orlando G, van der Kant R, Rousseau F, et al.
Bioinformatics
. 2025 Feb;
41(2).
PMID: 39913370
Motivation: The FoldX force field was originally validated with a database of 1000 mutants at a time when there were few high-resolution structures. Here, we have manually curated a database...
2.
Gurriaran-Rodriguez U, Datzkiw D, Radusky L, Esper M, Javandoost E, Xiao F, et al.
Sci Adv
. 2024 Dec;
10(50):eado5914.
PMID: 39661666
Wnt proteins are hydrophobic glycoproteins that are nevertheless capable of long-range signaling. We found that Wnt7a is secreted long distance on the surface of extracellular vesicles (EVs) following muscle injury....
3.
Ana Y, Gerngross D, Serrano L
Microb Cell Fact
. 2024 Nov;
23(1):306.
PMID: 39533283
The non-pathogenic Mycoplasma pneumoniae engineered chassis (Mycochassis) has demonstrated the ability to express therapeutic molecules in vitro and to be effective for treatment of lung infectious diseases in in vivo...
4.
Frutos-Grilo E, Ana Y, Gonzalez-de Miguel J, Cardona-I-Collado M, Rodriguez-Arce I, Serrano L
Mol Syst Biol
. 2024 Oct;
20(12):1261-1281.
PMID: 39443745
The genomic revolution has fueled rapid progress in synthetic and systems biology, opening up new possibilities for using live biotherapeutic products (LBP) to treat, attenuate or prevent human diseases. Among...
5.
Holtz A, Van Weyenbergh J, Hong S, Cuypers L, OToole A, Dudas G, et al.
BMC Infect Dis
. 2024 Oct;
24(1):1139.
PMID: 39390446
We investigate the emergence, mutation profile, and dissemination of SARS-CoV-2 lineage B.1.214.2, first identified in Belgium in January 2021. This variant, featuring a 3-amino acid insertion in the spike protein...
6.
Anglada-Girotto M, Ciampi L, Bonnal S, Head S, Miravet-Verde S, Serrano L
Nat Commun
. 2024 Aug;
15(1):7039.
PMID: 39147755
Alternative splicing is crucial for cancer progression and can be targeted pharmacologically, yet identifying driver exons genome-wide remains challenging. We propose identifying such exons by associating statistically gene-level cancer dependencies...
7.
Vicente A, Luna I, Ruiz J, Remigia M, Jerez A, Lluch R, et al.
Diagnostics (Basel)
. 2024 Aug;
14(15).
PMID: 39125507
The International Consensus Classification of Myeloid Neoplasms and Acute Leukemias (ICC) and the 5th edition of the WHO classification (WHO 2022) have refined the diagnosis of myelodysplastic syndromes (MDS). Both...
8.
Anglada-Girotto M, Moakley D, Zhang C, Miravet-Verde S, Califano A, Serrano L
bioRxiv
. 2024 Jul;
PMID: 38979366
Splicing factors control exon inclusion in messenger RNA, shaping transcriptome and proteome diversity. Their catalytic activity is regulated by multiple layers, making single-omic measurements on their own fall short in...
9.
Kourtis S, Cianferoni D, Serrano L, Sdelci S
Sci Data
. 2024 May;
11(1):551.
PMID: 38811611
Proteins are often referred to as the workhorses of cells, and their interactions are necessary to facilitate specific cellular functions. Despite the recognition that protein-protein interactions, and thus protein functions,...
10.
Gonzalez-de-Miguel J, Montero-Blay A, Ciampi L, Rodriguez-Arce I, Serrano L
Microb Cell Fact
. 2024 Apr;
23(1):124.
PMID: 38689251
Background: Having a simple and fast dividing organism capable of producing and exposing at its surface or secreting functional complex biomolecules with disulphide bridges is of great interest. The mycoplasma...