Tarjei S Mikkelsen
Overview
Explore the profile of Tarjei S Mikkelsen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
68
Citations
26936
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Tewhey R, Kotliar D, Park D, Liu B, Winnicki S, Reilly S, et al.
Cell
. 2016 Jun;
165(6):1519-1529.
PMID: 27259153
Although studies have identified hundreds of loci associated with human traits and diseases, pinpointing causal alleles remains difficult, particularly for non-coding variants. To address this challenge, we adapted the massively...
22.
OConnell D, Kolde R, Sooknah M, Graham D, Sundberg T, Latorre I, et al.
Cell Syst
. 2016 May;
2(5):323-334.
PMID: 27211859
Reporter gene assays are a venerable tool for studying signaling pathways, but they lack the throughput and complexity necessary to contribute to a systems-level understanding of endogenous signaling networks. We...
23.
Ferreira L, Meissner T, Mikkelsen T, Mallard W, ODonnell C, Tilburgs T, et al.
Proc Natl Acad Sci U S A
. 2016 Apr;
113(19):5364-9.
PMID: 27078102
HLA-G, a nonclassical HLA molecule uniquely expressed in the placenta, is a central component of fetus-induced immune tolerance during pregnancy. The tissue-specific expression of HLA-G, however, remains poorly understood. Here,...
24.
Cacchiarelli D, Trapnell C, Ziller M, Soumillon M, Cesana M, Karnik R, et al.
Cell
. 2015 Jul;
162(2):412-424.
PMID: 26186193
Induced pluripotency is a promising avenue for disease modeling and therapy, but the molecular principles underlying this process, particularly in human cells, remain poorly understood due to donor-to-donor variability and...
25.
Ziller M, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, et al.
Nature
. 2014 Dec;
518(7539):355-359.
PMID: 25533951
Models derived from human pluripotent stem cells that accurately recapitulate neural development in vitro and allow for the generation of specific neuronal subtypes are of major interest to the stem...
26.
Ulirsch J, Lacy J, An X, Mohandas N, Mikkelsen T, Sankaran V
PLoS Genet
. 2014 Dec;
10(12):e1004890.
PMID: 25521328
Erythropoiesis is one of the best understood examples of cellular differentiation. Morphologically, erythroid differentiation proceeds in a nearly identical fashion between humans and mice, but recent evidence has shown that...
27.
Kang S, Tsai L, Zhou Y, Evertts A, Xu S, Griffin M, et al.
Nat Cell Biol
. 2014 Dec;
17(1):44-56.
PMID: 25503565
Insulin resistance is a cardinal feature of Type 2 diabetes (T2D) and a frequent complication of multiple clinical conditions, including obesity, ageing and steroid use, among others. How such a...
28.
Matranga C, Andersen K, Winnicki S, Busby M, Gladden A, Tewhey R, et al.
Genome Biol
. 2014 Nov;
15(11):519.
PMID: 25403361
We have developed a robust RNA sequencing method for generating complete de novo assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and biological samples. Our...
29.
Melnikov A, Zhang X, Rogov P, Wang L, Mikkelsen T
J Vis Exp
. 2014 Sep;
(90).
PMID: 25177895
The genetic reporter assay is a well-established and powerful tool for dissecting the relationship between DNA sequences and their gene regulatory activities. The potential throughput of this assay has, however,...
30.
Schwartz S, Mumbach M, Jovanovic M, Wang T, Maciag K, Bushkin G, et al.
Cell Rep
. 2014 Jul;
8(1):284-96.
PMID: 24981863
N6-methyladenosine (m6A) is a common modification of mRNA with potential roles in fine-tuning the RNA life cycle. Here, we identify a dense network of proteins interacting with METTL3, a component...