Alexander Meissner
Overview
Explore the profile of Alexander Meissner including associated specialties, affiliations and a list of published articles.
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Articles
193
Citations
32611
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Recent Articles
1.
Hasenbein T, Hoelzl S, Smith Z, Gerhardinger C, Gonner M, Aguilar-Pimentel A, et al.
Nat Commun
. 2024 Dec;
15(1):10631.
PMID: 39638999
The lncRNA Crossfirre was identified as an imprinted X-linked gene, and is transcribed antisense to the trans-acting lncRNA Firre. The Firre locus forms an inactive-X-specific interaction with Dxz4, both loci...
2.
Smith Z, Hetzel S, Meissner A
Nat Rev Genet
. 2024 Aug;
26(1):7-30.
PMID: 39134824
The DNA methylation field has matured from a phase of discovery and genomic characterization to one seeking deeper functional understanding of how this modification contributes to development, ageing and disease....
3.
Guckelberger P, Doughty B, Munson G, Rao S, Tan Y, Cai X, et al.
bioRxiv
. 2024 Jul;
PMID: 39026740
Enhancers are key drivers of gene regulation thought to act via 3D physical interactions with the promoters of their target genes. However, genome-wide depletions of architectural proteins such as cohesin...
4.
Batki J, Hetzel S, Schifferl D, Bolondi A, Walther M, Wittler L, et al.
Nat Cell Biol
. 2024 Jun;
26(6):868-877.
PMID: 38849542
Despite a distinct developmental origin, extraembryonic cells in mice contribute to gut endoderm and converge to transcriptionally resemble their embryonic counterparts. Notably, all extraembryonic progenitors share a non-canonical epigenome, raising...
5.
Stotzel M, Cheng C, IIik I, Kumar A, Omgba P, van der Weijden V, et al.
Nat Struct Mol Biol
. 2024 May;
31(10):1625-1639.
PMID: 38783076
Dormancy is an essential biological process for the propagation of many life forms through generations and stressful conditions. Early embryos of many mammals are preservable for weeks to months within...
6.
Sato N, Rosa V, Makhlouf A, Kretzmer H, Kumar A, Grosswendt S, et al.
Dev Cell
. 2024 Apr;
59(10):1252-1268.e13.
PMID: 38579720
The blueprint of the mammalian body plan is laid out during gastrulation, when a trilaminar embryo is formed. This process entails a burst of proliferation, the ingression of embryonic epiblast...
7.
Bolondi A, Law B, Kretzmer H, Gassaloglu S, Buschow R, Riemenschneider C, et al.
Dev Cell
. 2024 Apr;
59(12):1489-1505.e14.
PMID: 38579718
Embryogenesis requires substantial coordination to translate genetic programs to the collective behavior of differentiating cells, but understanding how cellular decisions control tissue morphology remains conceptually and technically challenging. Here, we...
8.
Hauswedell H, Hetzel S, Gottlieb S, Kretzmer H, Meissner A, Reinert K
Bioinformatics
. 2024 Mar;
40(3).
PMID: 38485699
Motivation: Local alignments of query sequences in large databases represent a core part of metagenomic studies and facilitate homology search. Following the development of NCBI Blast, many applications aimed to...
9.
Mboni-Johnston I, Kouidrat N, Hirsch C, Weber A, Meissner A, Adjaye J, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203251
Proximal tubular epithelial cells (PTEC) are constantly exposed to potentially toxic metabolites and xenobiotics. The regenerative potential of the kidney enables the replacement of damaged cells either via the differentiation...
10.
Ravid Lustig L, Kumar A, Schwammle T, Dunkel I, Noviello G, Limberg E, et al.
Nat Cell Biol
. 2023 Nov;
25(11):1704-1715.
PMID: 37932452
X-chromosome inactivation (XCI) balances gene expression between the sexes in female mammals. Shortly after fertilization, upregulation of Xist RNA from one X chromosome initiates XCI, leading to chromosome-wide gene silencing....