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Stephan Kamrad

Explore the profile of Stephan Kamrad including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 293
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Recent Articles
1.
Rodriguez-Lopez M, Bordin N, Lees J, Scholes H, Hassan S, Saintain Q, et al.
Elife . 2023 Oct; 12. PMID: 37787768
Many proteins remain poorly characterized even in well-studied organisms, presenting a bottleneck for research. We applied phenomics and machine-learning approaches with for broad cues on protein functions. We assayed colony-growth...
2.
Hershey B, Barozzi S, Orsenigo F, Pompei S, Iannelli F, Kamrad S, et al.
Sci Adv . 2023 Sep; 9(37):eadh4184. PMID: 37713487
Cancers feature substantial intratumoral heterogeneity of genetic and phenotypically distinct lineages. Although interactions between coexisting lineages are emerging as a potential contributor to tumor evolution, the extent and nature of...
3.
Messner C, Demichev V, Muenzner J, Aulakh S, Barthel N, Rohl A, et al.
Cell . 2023 Apr; 186(9):2018-2034.e21. PMID: 37080200
Functional genomic strategies have become fundamental for annotating gene function and regulatory networks. Here, we combined functional genomics with proteomics by quantifying protein abundances in a genome-scale knockout library in...
4.
Kamrad S, Correia-Melo C, Szyrwiel L, Kaur Aulakh S, Bahler J, Demichev V, et al.
Nat Microbiol . 2023 Feb; 8(3):441-454. PMID: 36797484
Genetically identical cells are known to differ in many physiological parameters such as growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such phenotypic heterogeneity,...
5.
Gabrielli N, Maga-Nteve C, Kafkia E, Rettel M, Loeffler J, Kamrad S, et al.
Mol Syst Biol . 2023 Feb; 19(4):e11501. PMID: 36779294
Cross-feeding is fundamental to the diversity and function of microbial communities. However, identification of cross-fed metabolites is often challenging due to the universality of metabolic and biosynthetic intermediates. Here, we...
6.
Correia-Melo C, Kamrad S, Tengolics R, Messner C, Trebulle P, Townsend S, et al.
Cell . 2023 Jan; 186(1):63-79.e21. PMID: 36608659
Metabolism is deeply intertwined with aging. Effects of metabolic interventions on aging have been explained with intracellular metabolism, growth control, and signaling. Studying chronological aging in yeast, we reveal a...
7.
Kamrad S, Lindell A, Patil K
Nat Metab . 2022 Oct; 4(10):1219-1220. PMID: 36266545
No abstract available.
8.
Kamrad S, Bahler J, Ralser M
Methods Mol Biol . 2022 May; 2477:381-397. PMID: 35524128
Colony fitness screens are powerful approaches for functional genomics and genetics. This protocol describes experimental and computational procedures for assaying the fitness of thousands of microbial strains in numerous conditions...
9.
Rodriguez-Lopez M, Anver S, Cotobal C, Kamrad S, Malecki M, Correia-Melo C, et al.
Elife . 2022 Jan; 11. PMID: 35085068
No abstract available.
10.
Rodriguez-Lopez M, Anver S, Cotobal C, Kamrad S, Malecki M, Correia-Melo C, et al.
Elife . 2022 Jan; 11. PMID: 34984977
Eukaryotic genomes express numerous long intergenic non-coding RNAs (lincRNAs) that do not overlap any coding genes. Some lincRNAs function in various aspects of gene regulation, but it is not clear...