Michael Mulleder
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Explore the profile of Michael Mulleder including associated specialties, affiliations and a list of published articles.
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64
Citations
2119
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Recent Articles
1.
Kelm N, Kespohl M, Smagurauskaite G, Vales S, Karuppanan K, Mburu P, et al.
Basic Res Cardiol
. 2025 Feb;
PMID: 40009121
Myocarditis, an inflammatory disease of the heart muscle, is often triggered by viral infections. This inflammation, which can lead to severe cardiac dysfunction and adverse outcomes, is mediated by various...
2.
Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, Richter-Pechanska P, et al.
Nature
. 2025 Feb;
638(8052):E46.
PMID: 39905258
No abstract available.
3.
Buric F, Viknander S, Fu X, Lemke O, Carmona O, Zrimec J, et al.
Protein Sci
. 2024 Dec;
34(1):e5239.
PMID: 39665261
Understanding what drives protein abundance is essential to biology, medicine, and biotechnology. Driven by evolutionary selection, an amino acid sequence is tailored to meet the required abundance of a proteome,...
4.
Hantikainen E, Weichenberger C, Dordevic N, Verri Hernandes V, Foco L, Gogele M, et al.
Sci Rep
. 2024 Nov;
14(1):26635.
PMID: 39496618
Identifying biomarkers able to discriminate individuals on different health trajectories is crucial to understand the molecular basis of age-related morbidity. We investigated multi-omics signatures of general health and organ-specific morbidity,...
5.
Jakobson C, Hartl J, Trebulle P, Mulleder M, Jarosz D, Ralser M
bioRxiv
. 2024 Nov;
PMID: 39484408
Despite abundant genomic and phenotypic data across individuals and environments, the functional impact of most mutations on phenotype remains unclear. Here, we bridge this gap by linking genome to proteome...
6.
Zerbib J, Ippolito M, Eliezer Y, De Feudis G, Reuveni E, Savir Kadmon A, et al.
Nat Commun
. 2024 Sep;
15(1):7772.
PMID: 39251587
Aneuploidy is a hallmark of human cancer, yet the molecular mechanisms to cope with aneuploidy-induced cellular stresses remain largely unknown. Here, we induce chromosome mis-segregation in non-transformed RPE1-hTERT cells and...
7.
Ippolito M, Zerbib J, Eliezer Y, Reuveni E, Vigano S, De Feudis G, et al.
Cancer Discov
. 2024 Sep;
14(12):2532-2553.
PMID: 39247952
Aneuploidy results in a stoichiometric imbalance of protein complexes that jeopardizes cellular fitness. Aneuploid cells thus need to compensate for the imbalanced DNA levels by regulating their RNA and protein...
8.
Hansmann G, Chouvarine P, Diekmann F, Giera M, Ralser M, Mulleder M, et al.
Nat Cardiovasc Res
. 2024 Aug;
1(6):568-576.
PMID: 39195868
Here we report application of human umbilical cord mesenchymal stem cell (HUCMSC)-derived therapy for pulmonary arterial hypertension (PAH). A 3-year-old female presented with heritable PAH associated with hereditary hemorrhagic telangiectasia...
9.
Demirci H, Popovic S, Dittmayer C, Yilmaz D, El-Shimy I, Mulleder M, et al.
Acta Physiol (Oxf)
. 2024 Jun;
240(8):e14190.
PMID: 38884453
Aim: Calcineurin inhibitors (CNIs) are the backbone for immunosuppression after solid organ transplantation. Although successful in preventing kidney transplant rejection, their nephrotoxic side effects contribute to allograft injury. Renal parenchymal...
10.
Muenzner J, Trebulle P, Agostini F, Zauber H, Messner C, Steger M, et al.
Nature
. 2024 May;
630(8015):149-157.
PMID: 38778096
Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions and allows the generalizability of laboratory findings to be assessed. One notable discovery made in natural...