StJohn Townsend
Overview
Explore the profile of StJohn Townsend including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
173
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Recent Articles
1.
Grochowski M, Lipinska-Zubrycka L, Townsend S, Golisz-Mocydlarz A, Zakrzewska-Placzek M, Brzyzek G, et al.
Nat Commun
. 2024 Sep;
15(1):8359.
PMID: 39333464
Cytoplasmic mRNA decay is effected by exonucleolytic degradation in either the 5' to 3' or 3' to 5' direction. Pervasive terminal uridylation is implicated in mRNA degradation, however, its functional...
2.
Kern C, Srivastava S, Ezcurra M, Hsiung K, Hui N, Townsend S, et al.
Nat Commun
. 2023 Jul;
14(1):4381.
PMID: 37474586
In post-reproductive C. elegans, destructive somatic biomass repurposing supports production of yolk which, it was recently shown, is vented and can serve as a foodstuff for larval progeny. This is...
3.
Correia-Melo C, Kamrad S, Tengolics R, Messner C, Trebulle P, Townsend S, et al.
Cell
. 2023 Jan;
186(1):63-79.e21.
PMID: 36608659
Metabolism is deeply intertwined with aging. Effects of metabolic interventions on aging have been explained with intracellular metabolism, growth control, and signaling. Studying chronological aging in yeast, we reveal a...
4.
Wang Z, Cryar A, Lemke O, Tober-Lau P, Ludwig D, Helbig E, et al.
EClinicalMedicine
. 2022 Jun;
49:101495.
PMID: 35702332
Background: Global healthcare systems continue to be challenged by the COVID-19 pandemic, and there is a need for clinical assays that can help optimise resource allocation, support treatment decisions, and...
5.
Rodriguez-Lopez M, Anver S, Cotobal C, Kamrad S, Malecki M, Correia-Melo C, et al.
Elife
. 2022 Jan;
11.
PMID: 35085068
No abstract available.
6.
Rodriguez-Lopez M, Anver S, Cotobal C, Kamrad S, Malecki M, Correia-Melo C, et al.
Elife
. 2022 Jan;
11.
PMID: 34984977
Eukaryotic genomes express numerous long intergenic non-coding RNAs (lincRNAs) that do not overlap any coding genes. Some lincRNAs function in various aspects of gene regulation, but it is not clear...
7.
Kern C, Townsend S, Salzmann A, Rendell N, Taylor G, Comisel R, et al.
Nat Commun
. 2021 Oct;
12(1):5801.
PMID: 34611154
The nematode Caenorhabditis elegans exhibits rapid senescence that is promoted by the insulin/IGF-1 signalling (IIS) pathway via regulated processes that are poorly understood. IIS also promotes production of yolk for...
8.
Romila C, Townsend S, Malecki M, Kamrad S, Rodriguez-Lopez M, Hillson O, et al.
Microb Cell
. 2021 Jul;
8(7):146-160.
PMID: 34250083
Ageing-related processes are largely conserved, with simple organisms remaining the main platform to discover and dissect new ageing-associated genes. Yeasts provide potent model systems to study cellular ageing owing their...
9.
Minnis C, Townsend S, Petschnigg J, Tinelli E, Bahler J, Russell C, et al.
Sci Rep
. 2021 Jul;
11(1):14198.
PMID: 34226631
No abstract available.
10.
Minnis C, Townsend S, Petschnigg J, Tinelli E, Bahler J, Russell C, et al.
Sci Rep
. 2021 Mar;
11(1):6332.
PMID: 33737578
Juvenile CLN3 disease is a recessively inherited paediatric neurodegenerative disorder, with most patients homozygous for a 1-kb intragenic deletion in CLN3. The btn1 gene is the Schizosaccharomyces pombe orthologue of...