Cristina Cotobal
Overview
Explore the profile of Cristina Cotobal including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
263
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Recent Articles
1.
Rodriguez-Lopez M, Anver S, Cotobal C, Kamrad S, Malecki M, Correia-Melo C, et al.
Elife
. 2022 Jan;
11.
PMID: 35085068
No abstract available.
2.
Rodriguez-Lopez M, Anver S, Cotobal C, Kamrad S, Malecki M, Correia-Melo C, et al.
Elife
. 2022 Jan;
11.
PMID: 34984977
Eukaryotic genomes express numerous long intergenic non-coding RNAs (lincRNAs) that do not overlap any coding genes. Some lincRNAs function in various aspects of gene regulation, but it is not clear...
3.
Ellis D, Reyes-Martin F, Rodriguez-Lopez M, Cotobal C, Sun X, Saintain Q, et al.
PLoS Genet
. 2021 Aug;
17(8):e1009784.
PMID: 34464389
Aberrant repair of DNA double-strand breaks can recombine distant chromosomal breakpoints. Chromosomal rearrangements compromise genome function and are a hallmark of ageing. Rearrangements are challenging to detect in non-dividing cell...
4.
Romila C, Townsend S, Malecki M, Kamrad S, Rodriguez-Lopez M, Hillson O, et al.
Microb Cell
. 2021 Jul;
8(7):146-160.
PMID: 34250083
Ageing-related processes are largely conserved, with simple organisms remaining the main platform to discover and dissect new ageing-associated genes. Yeasts provide potent model systems to study cellular ageing owing their...
5.
Kamrad S, Rodriguez-Lopez M, Cotobal C, Correia-Melo C, Ralser M, Bahler J
Elife
. 2020 Jun;
9.
PMID: 32543370
Microbial fitness screens are a key technique in functional genomics. We present an all-in-one solution, , for automating and improving data analysis pipelines associated with large-scale fitness screens, including image...
6.
Atkinson S, Marguerat S, Bitton D, Rodriguez-Lopez M, Rallis C, Lemay J, et al.
RNA
. 2018 Jun;
24(9):1195-1213.
PMID: 29914874
Long noncoding RNAs (lncRNAs), which are longer than 200 nucleotides but often unstable, contribute a substantial and diverse portion to pervasive noncoding transcriptomes. Most lncRNAs are poorly annotated and understood,...
7.
Rodriguez-Lopez M, Cotobal C, Fernandez-Sanchez O, Borbaran Bravo N, Oktriani R, Abendroth H, et al.
Wellcome Open Res
. 2017 Jun;
1:19.
PMID: 28612052
In the fission yeast the prevailing approach for gene manipulations is based on homologous recombination of a PCR product that contains genomic target sequences and a selectable marker. The CRISPR/Cas9...
8.
Cotobal C, Rodriguez-Lopez M, Duncan C, Hasan A, Yamashita A, Yamamoto M, et al.
Epigenetics Chromatin
. 2015 Aug;
8:28.
PMID: 26279681
Background: Heterochromatin is essential for chromosome segregation, gene silencing and genome integrity. The fission yeast Schizosaccharomyces pombe contains heterochromatin at centromeres, subtelomeres, and mating type genes, as well as at...
9.
Bitton D, Atkinson S, Rallis C, Smith G, Ellis D, Chen Y, et al.
Genome Res
. 2015 Apr;
25(6):884-96.
PMID: 25883323
Exon skipping is considered a principal mechanism by which eukaryotic cells expand their transcriptome and proteome repertoires, creating different splice variants with distinct cellular functions. Here we analyze RNA-seq data...
10.
Hasan A, Cotobal C, Duncan C, Mata J
PLoS Genet
. 2014 Nov;
10(11):e1004684.
PMID: 25375137
mRNA half-lives are transcript-specific and vary over a range of more than 100-fold in eukaryotic cells. mRNA stabilities can be regulated by sequence-specific RNA-binding proteins (RBPs), which bind to regulatory...