Vadim Demichev
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Explore the profile of Vadim Demichev including associated specialties, affiliations and a list of published articles.
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37
Citations
1948
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Recent Articles
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Dai C, Pfeuffer J, Wang H, Zheng P, Kall L, Sachsenberg T, et al.
Nat Methods
. 2024 Jul;
21(9):1603-1607.
PMID: 38965444
The volume of public proteomics data is rapidly increasing, causing a computational challenge for large-scale reanalysis. Here, we introduce quantms ( https://quant,ms.org/ ), an open-source cloud-based pipeline for massively parallel...
3.
Muenzner J, Trebulle P, Agostini F, Zauber H, Messner C, Steger M, et al.
Nature
. 2024 May;
630(8015):149-157.
PMID: 38778096
Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions and allows the generalizability of laboratory findings to be assessed. One notable discovery made in natural...
4.
Metatla I, Roger K, Chhuon C, Ceccacci S, Chapelle M, Pierre-Olivier Schmit , et al.
Clin Proteomics
. 2024 Mar;
21(1):22.
PMID: 38475715
Plasma proteomics holds immense potential for clinical research and biomarker discovery, serving as a non-invasive "liquid biopsy" for tissue sampling. Mass spectrometry (MS)-based proteomics, thanks to improvement in speed and...
5.
Huang J, Staes A, Impens F, Demichev V, Van Breusegem F, Gevaert K, et al.
Redox Biol
. 2023 Oct;
67:102908.
PMID: 37793239
Protein cysteinyl thiols are susceptible to reduction-oxidation reactions that can influence protein function. Accurate quantification of cysteine oxidation is therefore crucial for decoding protein redox regulation. Here, we present CysQuant,...
6.
Kleeman S, Thakir T, Demestichas B, Mourikis N, Loiero D, Ferrer M, et al.
Cell Genom
. 2023 Aug;
3(8):100347.
PMID: 37601967
Cystatin C (CyC), a secreted cysteine protease inhibitor, has unclear biological functions. Many patients exhibit elevated plasma CyC levels, particularly during glucocorticoid (GC) treatment. This study links GCs with CyC's...
7.
Yang K, Yu F, Teo G, Li K, Demichev V, Ralser M, et al.
Nat Commun
. 2023 Jul;
14(1):4539.
PMID: 37500632
Peptide identification in liquid chromatography-tandem mass spectrometry (LC-MS/MS) experiments relies on computational algorithms for matching acquired MS/MS spectra against sequences of candidate peptides using database search tools, such as MSFragger....
8.
White M, Sinn L, Jones D, de Folter J, Kaur Aulakh S, Wang Z, et al.
Nat Biomed Eng
. 2023 Jul;
8(3):233-247.
PMID: 37474612
Protein glycosylation, a complex and heterogeneous post-translational modification that is frequently dysregulated in disease, has been difficult to analyse at scale. Here we report a data-independent acquisition technique for the...
9.
Yu F, Teo G, Kong A, Frohlich K, Li G, Demichev V, et al.
Nat Commun
. 2023 Jul;
14(1):4154.
PMID: 37438352
Liquid chromatography (LC) coupled with data-independent acquisition (DIA) mass spectrometry (MS) has been increasingly used in quantitative proteomics studies. Here, we present a fast and sensitive approach for direct peptide...
10.
Szyrwiel L, Gille C, Mulleder M, Demichev V, Ralser M
Proteomics
. 2023 Jun;
24(1-2):e2300100.
PMID: 37287406
Increased throughput in proteomic experiments can improve accessibility of proteomic platforms, reduce costs, and facilitate new approaches in systems biology and biomedical research. Here we propose combination of analytical flow...