Santhosh Satapati
Overview
Explore the profile of Santhosh Satapati including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
1899
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mukherjee S, McCaw Z, Pei J, Merkoulovitch A, Soare T, Tandon R, et al.
Bioinform Adv
. 2024 Dec;
4(1):vbae135.
PMID: 39664859
Summary: Machine learning-derived embeddings are a compressed representation of high content data modalities. Embeddings can capture detailed information about disease states and have been qualitatively shown to be useful in...
2.
Satapati S, Downes D, Metzger D, Shankaran H, Talukdar S, Zhou Y, et al.
SLAS Discov
. 2022 Jan;
27(1):20-28.
PMID: 35058172
Screening campaigns, especially those aimed at modulating enzyme activity, often rely on measuring substrate→product conversions. Unfortunately, the presence of endogenous substrates and/or products can limit one's ability to measure conversions....
3.
Wen X, Liu C, Ghislain L, Tovar K, Shah V, Stout S, et al.
Anal Chem
. 2021 Apr;
93(15):6071-6079.
PMID: 33819010
The primary goal of high-throughput screening (HTS) is to rapidly survey a broad collection of compounds, numbering from tens of thousands to millions of members, and identify those that modulate...
4.
Downes D, Zhong W, Zhang J, Chen B, Satapati S, Metzger D, et al.
J Am Soc Mass Spectrom
. 2020 Aug;
31(12):2421-2425.
PMID: 32840373
Spatial characterization of triglyceride metabolism is an area of significant interest which can be enabled by mass spectrometry imaging via recent advances in neutral lipid laser desorption analytical approaches. Here,...
5.
Chaurasia B, Tippetts T, Monibas R, Liu J, Li Y, Wang L, et al.
Science
. 2019 Jul;
365(6451):386-392.
PMID: 31273070
Ceramides contribute to the lipotoxicity that underlies diabetes, hepatic steatosis, and heart disease. By genetically engineering mice, we deleted the enzyme dihydroceramide desaturase 1 (DES1), which normally inserts a conserved...
6.
Fletcher J, Deja S, Satapati S, Fu X, Burgess S, Browning J
JCI Insight
. 2019 Apr;
5.
PMID: 31012869
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, and potentially morbid, disease that affects one-third of the U.S. population. Normal liver safely accommodates lipid excess during fasting or carbohydrate...
7.
Wu C, Satapati S, Gui W, Wynn R, Sharma G, Lou M, et al.
J Biol Chem
. 2018 May;
293(25):9604-9613.
PMID: 29739849
The pyruvate dehydrogenase complex (PDC) is a key control point of energy metabolism and is subject to regulation by multiple mechanisms, including posttranslational phosphorylation by pyruvate dehydrogenase kinase (PDK). Pharmacological...
8.
More V, Lao J, McLaren D, Cumiskey A, Murphy B, Chen Y, et al.
PLoS One
. 2017 Oct;
12(10):e0186586.
PMID: 29065174
Lipid lowering properties of glucagon have been reported. Blocking glucagon signaling leads to rise in plasma LDL levels. Here, we demonstrate the lipid lowering effects of acute dosing with Glp1r/Gcgr...
9.
Wang S, Satapati S, Daurio N, Kelley D, Previs S
Am J Physiol Endocrinol Metab
. 2017 Aug;
313(2):E259-E261.
PMID: 28794100
No abstract available.
10.
Satapati S, Qian Y, Wu M, Petrov A, Dai G, Wang S, et al.
J Lipid Res
. 2017 Jun;
58(8):1561-1578.
PMID: 28583918
GPR40 and GPR120 are fatty acid sensors that play important roles in glucose and energy homeostasis. GPR40 potentiates glucose-dependent insulin secretion and demonstrated in clinical studies robust glucose lowering in...