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American Journal of Physiology. Endocrinology and Metabolism

The American Journal of Physiology - Endocrinology and Metabolism is a renowned scientific journal that publishes cutting-edge research in the field of endocrinology and metabolism. It covers a wide range of topics including hormone regulation, metabolic pathways, and the physiological mechanisms underlying various endocrine disorders. With its rigorous peer-review process and high-quality articles, this journal serves as a valuable resource for researchers, clinicians, and students interested in understanding the intricate workings of the endocrine system and its impact on metabolism.

Details
Abbr. Am J Physiol Endocrinol Metab
Start 1980
End Continuing
Frequency Twice monthly, Feb. 2012-
p-ISSN 0193-1849
e-ISSN 1522-1555
Country United States
Language English
Metrics
h-index / Ranks: 508 224
SJR / Ranks: 2005 1479
CiteScore / Ranks: 1240 10.70
JIF / Ranks: 1521 5.1
Recent Articles
1.
Picoli C, Tsibulnikov S, Ho M, Demambro V, Feng T, Eltahir M, et al.
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40072928
Obesity is a global health challenge associated with significant metabolic and cardiovascular risks. Bariatric surgery and GLP-1 receptor agonists (GLP-1RAs) are effective interventions for weight loss and metabolic improvement, yet...
2.
Biagioni E, Rowe 4th J, Yendamuri S, Wisseman B, Zheng D, Zhang G, et al.
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40072921
Offspring exposed to metformin treatment for gestational diabetes mellitus (GDM) experience altered growth patterns that increase the risk for developing cardiometabolic diseases later in life. The adaptive cellular mechanisms underlying...
3.
Zangerolamo L, Carvalho M, Solon C, Sidarta-Oliveira D, Soares G, Marmentini C, et al.
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40059865
Fibroblast growth factor 19 (FGF19) signaling in the brain is associated with body weight loss, reduced food intake, and improved glycemic control in obese mice through unclear mechanisms. Here, we...
4.
Lin Z, Xuan Y, Zhang Y, Zhou Q, Qiu W
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40047236
The central nervous system (CNS) senses and integrates blood glucose status, regulating its levels through communication with peripheral organs. While traditional wisdom holds that the hypothalamus primarily controls glucose homeostasis,...
5.
Wang Y, Sanyal A, Hylemon P, Ren S
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40047198
Mitochondrial oxysterols, cholestenoic acid (CA), 25-hydroxycholesterol (25HC), and 27-hydroxycholesterol (27HC), are potent regulators involved in many important biological events. This study aimed to investigate the metabolic pathways of these oxysterols...
6.
Reed R, Zelek W, Morgan B, Whelehan G, Lockhart S, ORahilly S, et al.
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40047170
Populations of Black African (BA) ancestry are disproportionately affected by cardiometabolic diseases, possibly due to dysregulation of the complement system. This study aimed to determine 1) relationships between fasting complement...
7.
Oliveira K, Soares G, Silva Junior J, Alves B, Freitas I, Bem K, et al.
Am J Physiol Endocrinol Metab . 2025 Feb; PMID: 40019118
Insufficient or imbalanced protein can disrupt gut microbiota, potentially compromising gut barrier function and increasing health risks. Herein, we investigated the effects of protein restriction on cecal microbiota and colon...
8.
Mott J, Adin C, Crews C, Salute M, Tardo A, Porter L, et al.
Am J Physiol Endocrinol Metab . 2025 Feb; PMID: 40013934
In health, insulin-induced-hypoglycemia (IIH) activates counterregulatory hormones responses and parasympathetic (PS) and sympathoadrenal systems which leads to increased glucagon secretion. In diabetes mellitus, these responses are impaired, resulting in greater...
9.
Blok N, Myronovych A, McMahon G, Bozadjieva-Kramer N, Seeley R
Am J Physiol Endocrinol Metab . 2025 Feb; PMID: 39998384
Obesity induction in mice requires high-fat diet exposure. While hepatic steatosis develops, progression to inflammation and fibrosis, as in humans, requires prolonged exposure and additional dietary factors. Immunosuppression at room...
10.
Shin J, Bozadjieva-Kramer N, Shao Y, Shao Y, Mercer A, Lyons-Abbott S, et al.
Am J Physiol Endocrinol Metab . 2025 Feb; 328(3):E447-E456. PMID: 39970263
Regenerating islet-derived protein 3 gamma (Reg3g), a gut peptide has been implicated in host defense and various physiological functions including metabolic regulation. Emerging evidence has demonstrated that peripheral administration of...