Slas Discovery : Advancing Life Sciences R & D
Overview
Slas Discovery : Advancing Life Sciences R & D is a scientific journal, published by Sage Publications since 2017 in English. The journal's country of origin is United States and its primary focus area is molecular biology.
Details
Details
Abbr.
SLAS Discov
Publisher
Sage Publications
Start
2017
End
Continuing
Frequency
Ten times a year
p-ISSN
2472-5552
e-ISSN
2472-5560
Country
United States
Language
English
Specialty
Molecular Biology
Metrics
Metrics
h-index / Ranks: 9912
33
SJR / Ranks: 4687
869
CiteScore / Ranks: 3428
6.40
JIF / Ranks: 3327
3.1
Recent Articles
1.
Bradley J, OShea P, Wrench C, Mattsson J, Paulin R, Overed-Sayer C, et al.
SLAS Discov
. 2025 Mar;
32:100223.
PMID: 40024445
Senescent cells contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF), a disease with significant unmet need and therefore, there is an interest in discovering new drug targets that regulate...
2.
Mayfield A, Zhang X, Efremov I, Kauffman M, Reilly J, Eftekharzadeh B
SLAS Discov
. 2025 Mar;
32:100224.
PMID: 40024444
Biomolecular condensates (BMCs) are crucial for cellular organization and function, and their dysregulation is linked to neurological, oncologic and inflammatory diseases. This highlights the need for advanced investigative tools leading...
3.
Dexheimer T, Davoudi Z, Coussens N, Silvers T, Morris J, Takebe N, et al.
SLAS Discov
. 2025 Feb;
32:100222.
PMID: 39999911
Dysregulation of the phosphatidylinositol 3-kinase (PI3K) pathway is a key contributor to cancer, making PI3K inhibitors a promising approach for targeted therapy. The selectivity of available inhibitors varies across different...
4.
Bharath N, DiPietro E, Durfee O, Kycia I, Splaine J, Splaine J, et al.
SLAS Discov
. 2025 Feb;
32:100221.
PMID: 39947627
Fibrolamellar carcinoma (FLC) is a primary liver cancer with a poor prognosis, primarily due to the lack of effective chemotherapeutic options. The DNAJB1-PRKACA (DP) gene fusion is recognized as the...
5.
Quek R, Shirazinejad C, Young C, Hardy K, Lim S, Elms P, et al.
SLAS Discov
. 2025 Feb;
31:100220.
PMID: 39894078
Protein-nucleic acid phase separation has been implicated in many diseases such as viral infections, neurodegeneration, and cancer. There is great interest in identifying condensate modulators (CMODs), which are small molecules...
6.
Romaniello D, DallOlio L, Mazzeschi M, Francia A, Pagano F, Gelfo V, et al.
SLAS Discov
. 2025 Feb;
31:100219.
PMID: 39892619
A direct connection between an inflammatory environment and cancer has been extensively proven over the years. We previously reported that the presence of interleukin 1 (IL-1) is responsible for the...
7.
Dariolli R, Nir R, Mushlam T, Souza G, Farmer S, Batista Jr M
SLAS Discov
. 2025 Jan;
31:100218.
PMID: 39870353
Obesity and type 2 diabetes (T2D) are strongly linked to abnormal adipocyte metabolism and adipose tissue (AT) dysfunction. However, existing adipose tissue models have limitations, particularly in the stable culture...
8.
Chin S, Gallego P, Aagaard A, Carmen S, Barrett N, Wolny M, et al.
SLAS Discov
. 2025 Jan;
31:100216.
PMID: 39832740
Neurotrophic factor 3 (NTF3) is a cysteine knot protein and a member of the nerve growth factor (NGF) family of cytokines. NTF3 engages the Trk family of receptor tyrosine kinases,...
9.
Lundquist K, Romeo I, Puglielli R, Pestalozzi M, Gram M, Hudson E, et al.
SLAS Discov
. 2025 Jan;
31:100215.
PMID: 39828142
Fragment-based screening is an efficient method for early-stage drug discovery. In this study, we aimed to create a fragment library optimized for producing high hit rates against RNA targets. RNA...
10.
Schwalm M, Knapp S
SLAS Discov
. 2025 Jan;
31:100214.
PMID: 39826872
Cancer research, cancer treatment, and the field of chemical biology are examples which heavily rely on the discovery of selective kinase inhibitors. While determining on-target potency is often feasible for...