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Journal of Lipid Research

The Journal of Lipid Research is a leading scientific publication dedicated to advancing the understanding of lipids and their role in various biological processes. It features cutting-edge research articles, reviews, and perspectives that explore lipid metabolism, lipidomics, lipid signaling, and lipid-related diseases. This interdisciplinary journal serves as a valuable resource for researchers, clinicians, and students interested in lipid biology and its implications for human health.

Details
Abbr. J Lipid Res
Publisher Elsevier
Start 1959
End Continuing
Frequency Monthly
p-ISSN 0022-2275
e-ISSN 1539-7262
Country United States
Language English
Specialty Biochemistry
Metrics
h-index / Ranks: 519 223
SJR / Ranks: 1117 2090
CiteScore / Ranks: 1018 11.70
JIF / Ranks: 979 6.5
Recent Articles
1.
Lee S, Hong K, Park B, Jung D
J Lipid Res . 2025 Mar; :100777. PMID: 40089108
Recent studies have shown that hyper-HDL-cholesterol (HDL-C) is associated with cardiovascular disease (CVD) risk and all-cause mortality, a phenomenon known as the HDL-C paradox. Several genes have been reported to...
2.
Ao L, van Heemst D, Jukema J, Rensen P, Willems van Dijk K, Noordam R
J Lipid Res . 2025 Mar; :100778. PMID: 40089107
Background: Plasma 1-H nuclear magnetic resonance (H-NMR) metabolomic measures have yielded significant insight into the pathophysiology of cardiometabolic disease, but their interrelated nature complicates causal inference and clinical interpretation. This...
3.
Bai G, Ke S, Lu J, Yu S, Li S, Fang M, et al.
J Lipid Res . 2025 Mar; :100776. PMID: 40086696
Metabolic reprogramming is often observed in sepsis-associated microglial cells. However, little is known about the aberrant metabolic genes involved in neuroinflammation and lipid accumulation in microglial cells of sepsis-associated encephalopathy...
4.
Gonzalez-Nieves S, Wei X, Guignard S, Nguyen T, McQuillan J, Zhang Q, et al.
J Lipid Res . 2025 Mar; :100775. PMID: 40081576
Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and vessel maintenance. Altered lipid metabolism is associated with loss of lymphatic vessel integrity, which compromises organ function,...
5.
Yaghmour M, Sajeevan T, Thiele C, Kuerschner L
J Lipid Res . 2025 Mar; :100773. PMID: 40074037
Mammalian cells synthesize hundreds of different variants of their prominent membrane lipid phosphatidylcholine (PC), all differing in the side chain composition. This batch is constantly remodeled by the Lands cycle,...
6.
Tanwar V, Reddy M, Dey S, Malek V, Lanting L, Chen Z, et al.
J Lipid Res . 2025 Mar; :100774. PMID: 40068774
Free fatty acids like palmitic acid (PA) are elevated in obesity and diabetes and dysregulate monocyte and macrophage functions, contributing to enhanced inflammation in these cardiometabolic diseases. Epigenetic mechanisms regulating...
7.
Huo F, Liu C, Wang X, Li J, Wang Z, Liu D, et al.
J Lipid Res . 2025 Mar; :100772. PMID: 40058593
Obesity is a prevalent global disease associated with various metabolic disorders. The expansion of white adipose tissue plays a pivotal role in regulating obesity-related metabolic dysfunctions. This study identified serum-defined...
8.
Omri S, Argyriou C, Pryce R, Di Pietro E, Chaurand P, Braverman N
J Lipid Res . 2025 Mar; :100771. PMID: 40058592
Zellweger Spectrum Disorder (ZSD) is caused by defects in PEX genes, whose proteins are required for peroxisome assembly and function. Peroxisome dysfunction in ZSD causes multisystem effects, with progressive retinal...
9.
Grytten E, Laupsa-Borge J, Cetin K, Bohov P, Nordrehaug J, Skorve J, et al.
J Lipid Res . 2025 Mar; :100770. PMID: 40058591
n-3 (e.g., EPA/DHA) and n-6 (e.g., LA) fatty acids are suggested to have opposite effects on inflammation, but results are inconsistent and direct comparisons of n-3 and n-6 are lacking....
10.
Luetzen M, Chakraborty R, Moreno-Ramos O, Echeverri-Pena O, Satta Y, Montano A
J Lipid Res . 2025 Mar; :100769. PMID: 40054667
The myelin is responsible for providing stability to the axons of the nerve cells, but above all to improve transmission speed of the nerve impulse in vertebrates. Over 70% of...