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Rene L Jacobs

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Articles 93
Citations 2702
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Recent Articles
1.
A Elmihi K, Leonard K, Nelson R, Thiesen A, Clugston R, Jacobs R
FASEB J . 2024 Sep; 38(18):e70063. PMID: 39312446
Ethanolamine phosphate phospholyase (ETNPPL) is an enzyme that irreversibly degrades phospho-ethanolamine (p-ETN), an intermediate in the Kennedy pathway of phosphatidylethanolamine (PE) biosynthesis. PE is the second most abundant phospholipid in...
2.
Rusnak T, Azarcoya-Barrera J, Makarowski A, Jacobs R, Richard C
J Nutr . 2024 Apr; 154(6):1936-1944. PMID: 38582387
Background: Phosphatidylcholine (PC) derived from eggs has been shown to beneficially modulate T cell response and intestinal permeability under the context of a high-fat diet. Objectives: The objective of this...
3.
Azarcoya-Barrera J, Wollin B, Veida-Silva H, Makarowski A, Goruk S, Field C, et al.
Front Nutr . 2023 Oct; 10:1304098. PMID: 37899832
[This corrects the article DOI: 10.3389/fnut.2022.811469.].
4.
Azarcoya-Barrera J, Field C, Goruk S, Makarowski A, Curtis J, Pouliot Y, et al.
Eur J Nutr . 2023 Oct; 63(1):339. PMID: 37847401
No abstract available.
5.
Rusnak T, Azarcoya-Barrera J, Wollin B, Makarowski A, Nelson R, Field C, et al.
J Nutr . 2023 Aug; 153(10):3131-3143. PMID: 37586605
Background: Obesity is associated with increased intestinal permeability and a diminished immune response. Phosphatidylcholine (PC), a form of choline found in eggs, has been shown to beneficially modulate T-cell response...
6.
Azarcoya-Barrera J, Lewis E, Field C, Goruk S, Makarowski A, Pouliot Y, et al.
J Nutr . 2023 Feb; 152(11):2604-2614. PMID: 36774126
Background: In humans, the development of gut-associated lymphoid tissue (GALT) occurs in the first years of life and can be influenced by diet. Objectives: The objective of this study was...
7.
Trzaskalski N, Vulesevic B, Nguyen M, Jeraj N, Fadzeyeva E, Morrow N, et al.
JCI Insight . 2022 Dec; 8(2). PMID: 36472923
Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty liver disease progression remains unclear. Here, we identified that DPP4...
8.
Uehara K, Sostre-Colon J, Gavin M, Santoleri D, Leonard K, Jacobs R, et al.
Cell Mol Gastroenterol Hepatol . 2022 Mar; 13(6):1625-1647. PMID: 35240344
Background & Aims: Dysregulation of liver lipid metabolism is associated with the development and progression of nonalcoholic fatty liver disease, a spectrum of liver diseases including nonalcoholic steatohepatitis (NASH). In...
9.
Azarcoya-Barrera J, Wollin B, Veida-Silva H, Makarowski A, Goruk S, Field C, et al.
Front Nutr . 2022 Feb; 9:811469. PMID: 35187037
Obesity is associated with immune dysfunction including an impaired T-cell function characterized by a lower IL-2 (proliferation marker) production after stimulation. Phosphatidylcholine (PC), a form of choline mostly found in...
10.
Christensen K, Malysheva O, Carlin S, Matias F, MacFarlane A, Jacobs R, et al.
Nutrients . 2022 Jan; 14(1). PMID: 35011003
Folate and choline are interconnected metabolically. The MTHFD1 R653Q SNP is a risk factor for birth defects and there are concerns that choline deficiency may interact with this SNP and...