Paul B Rothman
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Explore the profile of Paul B Rothman including associated specialties, affiliations and a list of published articles.
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2486
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Recent Articles
11.
12.
Levine A, Alpern R, Andrews N, Antman K, Balser J, Berg J, et al.
Sci Transl Med
. 2015 May;
7(289):289fs22.
PMID: 26019216
Reductions in federal support and clinical revenue jeopardize biomedical research and, in turn, clinical medicine.
13.
Li Y, Chen H, Bannick N, Henry M, Holm A, Metwali A, et al.
J Immunol
. 2014 Dec;
194(3):1011-20.
PMID: 25527786
Donor T lymphocyte transfer with hematopoietic stem cells suppresses residual tumor growth (graft-versus-tumor [GVT]) in cancer patients undergoing bone marrow transplantation (BMT). However, donor T cell reactivity to host organs...
14.
Pronovost P, Armstrong C, Demski R, Callender T, Winner L, Miller M, et al.
Acad Med
. 2014 Dec;
90(2):165-72.
PMID: 25517699
In this article, the authors describe an initiative that established an infrastructure to manage quality and safety efforts throughout a complex health care system and that improved performance on core...
15.
Sojka D, Plougastel-Douglas B, Yang L, Pak-Wittel M, Artyomov M, Ivanova Y, et al.
Elife
. 2014 Apr;
3:e01659.
PMID: 24714492
Natural killer (NK) cells belong to the innate immune system; they can control virus infections and developing tumors by cytotoxicity and producing inflammatory cytokines. Most studies of mouse NK cells,...
16.
Gorman J, Starbeck-Miller G, Pham N, Traver G, Rothman P, Harty J, et al.
J Immunol
. 2014 Feb;
192(7):3133-42.
PMID: 24567532
T cell Ig and mucin domain (Tim) 3 is a surface molecule expressed throughout the immune system that can mediate both stimulatory and inhibitory effects. Previous studies have provided evidence...
17.
Kobayashi T, Steinbach E, Russo S, Matsuoka K, Nochi T, Maharshak N, et al.
J Immunol
. 2014 Jan;
192(4):1918-27.
PMID: 24442434
NFIL3 is a transcription factor that regulates multiple immunologic functions. In myeloid cells, NFIL3 is IL-10 inducible and has a key role as a repressor of IL-12p40 transcription. NFIL3 is...
18.
Firth M, Madera S, Beaulieu A, Gasteiger G, Castillo E, Schluns K, et al.
J Exp Med
. 2013 Nov;
210(13):2981-90.
PMID: 24277151
Development of the natural killer (NK) cell lineage is dependent on the transcription factor Nfil3 (or E4BP4), which is thought to act downstream of IL-15 signaling. Nfil3-deficient mice lack NK...
19.
Yu X, Rollins D, Ruhn K, Stubblefield J, Green C, Kashiwada M, et al.
Science
. 2013 Nov;
342(6159):727-30.
PMID: 24202171
Circadian clocks regulate numerous physiological processes that vary across the day-night (diurnal) cycle, but if and how the circadian clock regulates the adaptive immune system is mostly unclear. Interleukin-17-producing CD4(+)...
20.
Capuano M, Sorkin J, Chang Y, Ling H, OConnell J, Rothman P, et al.
BMC Res Notes
. 2013 Jun;
6:235.
PMID: 23767996
Background: SOCS7 is a member of the suppressor of cytokine signaling family of proteins and is expressed in skeletal muscle and islets. SOCS7 deficient mice develop islet hyperplasia in the...