Masaki Kashiwada
Overview
Explore the profile of Masaki Kashiwada including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
638
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Recent Articles
1.
ST2 gene products critically contribute to cellular transformation caused by an oncogenic Ras mutant
Tago K, Ohta S, Kashiwada M, Funakoshi-Tago M, Matsugi J, Tominaga S, et al.
Heliyon
. 2017 Dec;
3(10):e00436.
PMID: 29226265
The ST2 gene was originally identified as a primary responsive gene, and the expressions of its gene products are induced by stimulation with growth factors and by oncogenic stresses. In...
2.
Kobayashi T, Steinbach E, Russo S, Matsuoka K, Nochi T, Maharshak N, et al.
J Immunol
. 2014 Jan;
192(4):1918-27.
PMID: 24442434
NFIL3 is a transcription factor that regulates multiple immunologic functions. In myeloid cells, NFIL3 is IL-10 inducible and has a key role as a repressor of IL-12p40 transcription. NFIL3 is...
3.
Yu X, Rollins D, Ruhn K, Stubblefield J, Green C, Kashiwada M, et al.
Science
. 2013 Nov;
342(6159):727-30.
PMID: 24202171
Circadian clocks regulate numerous physiological processes that vary across the day-night (diurnal) cycle, but if and how the circadian clock regulates the adaptive immune system is mostly unclear. Interleukin-17-producing CD4(+)...
4.
Qiu X, Guo G, Chen K, Kashiwada M, Druker B, Rothman P, et al.
Neoplasia
. 2012 Jul;
14(6):547-58.
PMID: 22787435
Suppressors of cytokine signaling 1 and 3 (SOCS-1 and SOCS-3) are inhibitors of the Janus tyrosine kinase (JAK)/signal transducers and activators of transcription (STAT) pathway and function in a negative...
5.
Hostager B, Kashiwada M, Colgan J, Rothman P
PLoS One
. 2011 Aug;
6(8):e23061.
PMID: 21829693
CD40 is a cell surface receptor important in the activation of antigen-presenting cells during immune responses. In macrophages and dendritic cells, engagement of CD40 by its ligand CD154 provides signals...
6.
Kashiwada M, Cassel S, Colgan J, Rothman P
EMBO J
. 2011 Apr;
30(10):2071-82.
PMID: 21499227
Type 2 T helper (T(H)2) cells are critical for the development of allergic immune responses; however, the molecular mechanism controlling their effector function is still largely unclear. Here, we report...
7.
Kashiwada M, Pham N, Pewe L, Harty J, Rothman P
Blood
. 2011 Apr;
117(23):6193-7.
PMID: 21474667
Antigen presentation by mature dendritic cells (DCs) is the first step for initiating adaptive immune responses. DCs are composed of heterogeneous functional subsets; however, the molecular mechanisms that regulate differentiation...
8.
Kobayashi T, Matsuoka K, Sheikh S, Elloumi H, Kamada N, Hisamatsu T, et al.
J Immunol
. 2011 Mar;
186(8):4649-55.
PMID: 21383239
Regulation of innate inflammatory responses against the enteric microbiota is essential for the maintenance of intestinal homeostasis. Key participants in innate defenses are macrophages. In these studies, the basic leucine...
9.
Kashiwada M, Levy D, McKeag L, Murray K, Schroder A, Canfield S, et al.
Proc Natl Acad Sci U S A
. 2010 Jan;
107(2):821-6.
PMID: 20080759
IL-4 signaling promotes IgE class switching through STAT6 activation and the induction of Ig germ-line epsilon (GLepsilon) transcription. Previously, we and others identified a transcription factor, Nfil3, as a gene...
10.
Kashiwada M, Lu P, Rothman P
Immunol Res
. 2007 Oct;
39(1-3):194-224.
PMID: 17917066
Regulatory T cells (Tregs) play an important role in preventing both autoimmune and inflammatory diseases. Many recent studies have focused on defining the signal transduction pathways essential for the development...