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Justin Mostecki

Explore the profile of Justin Mostecki including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 103
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Recent Articles
1.
Duquesnoy R, Marrari M, Mulder A, Claas F, Mostecki J, Balazs I
Hum Immunol . 2012 Jan; 73(3):267-77. PMID: 22227099
This study addresses the concept that human leukocyte antigen (HLA) class I-specific alloantibodies are specific for epitopes that correspond to HLAMatchmaker-defined eplets. Eplets are essential parts of so-called structural epitopes...
2.
Mostecki J, Cassel S, Klimecki W, Stern D, Knisz J, Iwashita S, et al.
J Immunol . 2011 Jul; 187(5):2794-802. PMID: 21795592
SOCS-1 is a critical regulator of multiple signaling pathways, including those activated by cytokines that regulate Ig H chain class switching to IgE. Analysis of mice with mutations in the...
3.
Marrari M, Mostecki J, Mulder A, Claas F, Balazs I, Duquesnoy R
Transplantation . 2010 Nov; 90(12):1468-72. PMID: 21063243
Aim: Humoral sensitization affects transplant outcome, and it is now apparent that human leukocyte antigen (HLA) antibodies are specific for epitopes rather than antigens. Such epitopes can be structurally defined...
4.
Duquesnoy R, Mostecki J, Hariharan J, Balazs I
Hum Immunol . 2008 Oct; 69(12):826-32. PMID: 18957310
Recent studies have suggested a clinical significance to the detection of anti-major histocompatibility complex class I-related chain A (MICA) antibodies in transplantation. We have developed an eplet-based version of the...
5.
Harris M, Mostecki J, Rothman P
J Biol Chem . 2005 Jan; 280(13):13114-21. PMID: 15659391
BCL-6 functions as a potent transcriptional repressor that binds with specificity to DNA elements bearing marked similarity to STAT recognition sequences. Previous studies have demonstrated that BCL-6 and Stat6 can...
6.
Mostecki J, Showalter B, Rothman P
J Biol Chem . 2004 Nov; 280(4):2596-605. PMID: 15545275
Suppressor of cytokine signaling (SOCS)-1 is a critical regulator of lipopolysaccharide (LPS) tolerance and LPS-induced cytokine production. The mechanisms regulating the transcription of SOCS-1 in response to LPS are not...
7.
Vuong B, Arenzana T, Showalter B, Losman J, Chen X, Mostecki J, et al.
Mol Cell Biol . 2004 Oct; 24(20):9092-101. PMID: 15456882
The regulation of cytokine signaling is critical for controlling cellular proliferation and activation during an immune response. SOCS-1 is a potent inhibitor of Jak kinase activity and of signaling initiated...