Michael R Blackburn
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Explore the profile of Michael R Blackburn including associated specialties, affiliations and a list of published articles.
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144
Citations
6532
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Recent Articles
1.
Wang W, Chen N, Ren D, Davies J, Philip K, Eltzschig H, et al.
Front Mol Biosci
. 2021 Mar;
8:636678.
PMID: 33778007
Acute respiratory distress syndrome (ARDS) is a clinical presentation of acute lung injury (ALI) with often fatal lung complication. Adenosine, a nucleoside generated following cellular stress provides protective effects in...
2.
Wongtrakool C, Ko J, Jang A, Grooms K, Chang S, Sylber C, et al.
J Biol Chem
. 2020 Oct;
295(52):18051-18064.
PMID: 33082140
Evolving evidence suggests that nicotine may contribute to impaired asthma control by stimulating expression of nerve growth factor (NGF), a neurotrophin associated with airway remodeling and airway hyperresponsiveness. We explored...
3.
Weng T, Huang J, Wagner E, Ko J, Wu M, Wareing N, et al.
J Exp Med
. 2019 Nov;
217(2).
PMID: 31757866
Systemic sclerosis (SSc; scleroderma) is a multisystem fibrotic disease. The mammalian cleavage factor I 25-kD subunit (CFIm25; encoded by NUDT21) is a key regulator of alternative polyadenylation, and its depletion...
4.
Ko J, Mills T, Huang J, Chen N, Mertens T, Collum S, et al.
J Biol Chem
. 2019 Sep;
294(43):15781-15794.
PMID: 31488543
Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by the pathological remodeling of air sacs as a result of excessive accumulation of extracellular matrix (ECM) proteins, but the mechanism...
5.
Ruan H, Xiang Y, Ko J, Li S, Jing Y, Zhu X, et al.
Genome Med
. 2019 Aug;
11(1):55.
PMID: 31446897
Background: Human cancer cell lines are fundamental models for cancer research and therapeutic strategy development. However, there is no characterization of circular RNAs (circRNAs) in a large number of cancer...
6.
Wu M, Skaug B, Bi X, Mills T, Salazar G, Zhou X, et al.
Ann Rheum Dis
. 2019 Aug;
78(11):1583-1591.
PMID: 31439591
Objectives: There is considerable evidence that implicates dysregulation of type I interferon signalling (or type I IFN signature) in the pathogenesis of systemic sclerosis (SSc). Interferon regulatory factor 7 (IRF7)...
7.
Collum S, Molina J, Hanmandlu A, Bi W, Pedroza M, Mertens T, et al.
Dis Model Mech
. 2019 May;
12(5).
PMID: 31036697
Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 ...
8.
Huang C, Xiao X, Yang Y, Mishra A, Liang Y, Zeng X, et al.
J Biol Chem
. 2019 Apr;
294(17):6694.
PMID: 31028163
No abstract available.
9.
Weng T, Ko J, Masamha C, Xia Z, Xiang Y, Chen N, et al.
J Clin Invest
. 2019 Mar;
129(5):1984-1999.
PMID: 30830875
Idiopathic pulmonary fibrosis (IPF) is a chronic and deadly disease with a poor prognosis and few treatment options. Pathological remodeling of the extracellular matrix (ECM) by myofibroblasts is a key...
10.
Aherne C, Collins C, Rapp C, Olli K, Perrenoud L, Jedlicka P, et al.
JCI Insight
. 2018 Oct;
3(20).
PMID: 30333323
Intestinal epithelial barrier repair is vital for remission in inflammatory bowel disease (IBD). Extracellular adenosine signaling has been implicated in promoting restoration of epithelial barrier function. Currently, no clinically approved...