Genome Medicine
Overview
Genome Medicine is a peer-reviewed open-access journal that focuses on the application of genomic and molecular biology research to advance personalized medicine. It publishes high-quality articles covering a wide range of topics, including genomics, transcriptomics, epigenomics, and systems medicine, with the aim of improving disease diagnosis, treatment, and prevention. The journal provides a platform for researchers, clinicians, and policymakers to share cutting-edge discoveries and insights in the rapidly evolving field of genomic medicine.
Details
Details
Abbr.
Genome Med
Publisher
Biomed Central
Start
2009
End
Continuing
e-ISSN
1756-994X
Country
United Kingdom
Language
English
Specialty
Genetics
Metrics
Metrics
h-index / Ranks: 2146
123
SJR / Ranks: 262
4975
CiteScore / Ranks: 450
17.90
JIF / Ranks: 320
12.3
Recent Articles
1.
Wang Y, Liu Z, Ma X
Genome Med
. 2025 Mar;
17(1):21.
PMID: 40082941
Spatially resolved transcriptomics (SRT) simultaneously measure spatial location, histology images, and transcriptional profiles of cells or regions in undissociated tissues. Integrative analysis of multi-modal SRT data holds immense potential for...
2.
Diricks M, Maurer F, Dreyer V, Barilar I, Utpatel C, Merker M, et al.
Genome Med
. 2025 Mar;
17(1):19.
PMID: 40038805
Background: Non-tuberculous mycobacteria (NTM) are a diverse group of environmental bacteria that are increasingly associated with human infections and difficult to treat. Plasmids, which might carry resistance and virulence factors,...
3.
Vialle R, de Paiva Lopes K, Li Y, Ng B, Schneider J, Buchman A, et al.
Genome Med
. 2025 Mar;
17(1):20.
PMID: 40038788
Background: Alzheimer's disease (AD) is a complex neurodegenerative disorder with substantial genetic influence. While genome-wide association studies (GWAS) have identified numerous risk loci for late-onset AD (LOAD), the functional mechanisms...
4.
Bennett J, Saint-Martin C, Neumann B, Mannisto J, Houghton J, Empting S, et al.
Genome Med
. 2025 Mar;
17(1):17.
PMID: 40033430
Background: We recently reported non-coding variants in a cis-regulatory element of the beta-cell disallowed gene hexokinase 1 (HK1) as a novel cause of congenital hyperinsulinism. These variants lead to a...
5.
Wang R, Qian Y, Guo X, Song F, Xiong Z, Cai S, et al.
Genome Med
. 2025 Mar;
17(1):18.
PMID: 40033360
Here we present STModule, a Bayesian method developed to identify tissue modules from spatially resolved transcriptomics that reveal spatial components and essential characteristics of tissues. STModule uncovers diverse expression signals...
6.
Zhan Y, Zhang Y, Hu Z, Wang Y, Zhu Z, Du S, et al.
Genome Med
. 2025 Feb;
17(1):16.
PMID: 40022231
Spatial transcriptomics (ST) enables the study of gene expression in spatial context, but many ST technologies face challenges due to limited resolution, leading to cell mixtures at each spot. We...
7.
Takahashi N, Pongor L, Agrawal S, Shtumpf M, Gurjar A, Rajapakse V, et al.
Genome Med
. 2025 Feb;
17(1):15.
PMID: 40001151
Background: Profiling circulating cell-free DNA (cfDNA) has become a fundamental practice in cancer medicine, but the effectiveness of cfDNA at elucidating tumor-derived molecular features has not been systematically compared to...
8.
Jiang J, Cienfuegos-Gallet A, Long T, Peirano G, Chu T, Pitout J, et al.
Genome Med
. 2025 Feb;
17(1):13.
PMID: 39994790
No abstract available.
9.
Sibony-Benyamini H, Jbara R, Shubash Napso T, Abu-Rahmoun L, Vizenblit D, Easton-Mor M, et al.
Genome Med
. 2025 Feb;
17(1):14.
PMID: 39994739
Background: Helicobacter pylori (H. pylori) infection is a significant risk factor for gastric cancer (GC) development. A growing body of evidence suggests a causal link between infection with H. pylori...
10.
Muffels I, Waterham H, DAlessandro G, Zagnoli-Vieira G, Sacher M, Lefeber D, et al.
Genome Med
. 2025 Feb;
17(1):12.
PMID: 39920830
Background: Deciphering variants of uncertain significance (VUS) represents a major diagnostic challenge, partially due to the lack of easy-to-use and versatile cellular readouts that aid the interpretation of pathogenicity and...