Holger K Eltzschig
Overview
Explore the profile of Holger K Eltzschig including associated specialties, affiliations and a list of published articles.
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296
Citations
16818
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Recent Articles
1.
Flynn C, Markey G, Neudecker V, Farrelly C, Furuta G, Eltzschig H, et al.
J Immunol
. 2024 Nov;
213(12):1869-1883.
PMID: 39485006
Aberrant intestinal inflammation plays a critical role in the development of colitis-associated colorectal cancer (CAC), yet the mechanisms controlling tumor development by the myeloid immune compartment are not fully understood....
2.
Dietz S, Hebel J, Ruhle J, Huff A, Eltzschig H, Lajqi T, et al.
Eur J Immunol
. 2024 Oct;
54(12):e2451149.
PMID: 39460389
During pregnancy, the maternal immune system must carefully balance protection against pathogens with tolerance toward the semiallogeneic fetus. Dysfunctions of the immune system can lead to severe complications such as...
3.
Czopik A, McNamee E, Vaughn V, Huang X, Bang I, Clark T, et al.
Nat Commun
. 2024 Sep;
15(1):8042.
PMID: 39271652
Metabolic imbalance leading to inflammatory hypoxia and stabilization of hypoxia-inducible transcription factors (HIFs) is a hallmark of inflammatory bowel diseases. We hypothesize that HIF could be stabilized in CD4 T...
4.
Strickland L, Liu W, Hussein U, Mardik N, Chen X, Mills T, et al.
Cancer Prev Res (Phila)
. 2024 Aug;
17(10):457-470.
PMID: 39099209
Immunoprevention is an emerging consideration for solid tumors, including pancreatic ductal adenocarcinoma (PDAC). We and others have shown that Kras mutations in genetic models of spontaneous pancreatic intraepithelial neoplasia (PanIN),...
5.
Yang Y, Xu L, Atkins C, Kuhlman L, Zhao J, Jeong J, et al.
Gut
. 2024 May;
73(9):1543-1553.
PMID: 38724220
Objective: Previous studies indicate that eosinophils are recruited into the allograft following orthotopic liver transplantation and protect from ischaemia reperfusion (IR) injury. In the current studies, we aim to explore...
6.
Ravel-Godreuil C, Roy E, Puttapaka S, Li S, Wang Y, Yuan X, et al.
Brain Sci
. 2024 Apr;
14(4).
PMID: 38671993
Brain hypoxia is associated with a wide range of physiological and clinical conditions. Although oxygen is an essential constituent of maintaining brain functions, our understanding of how specific brain cell...
7.
Ruan W, Li T, Lee J, Bang I, Deng W, Ma X, et al.
Res Sq
. 2024 Mar;
PMID: 38464103
Acute myocardial infarction stands as a prominent cause of morbidity and mortality worldwide. Clinical studies have demonstrated that the severity of cardiac injury following myocardial infarction exhibits a circadian pattern,...
8.
Lee S, Suh J, Heo M, Choi J, Yang Y, Jung H, et al.
Diabetes
. 2024 Feb;
73(5):701-712.
PMID: 38320268
Article Highlights:
9.
Yuan X, Ruan W, Bobrow B, Carmeliet P, Eltzschig H
Nat Rev Drug Discov
. 2023 Dec;
23(3):175-200.
PMID: 38123660
Hypoxia-inducible factors (HIFs) are highly conserved transcription factors that are crucial for adaptation of metazoans to limited oxygen availability. Recently, HIF activation and inhibition have emerged as therapeutic targets in...
10.
Tran T, Eltzschig H, Yuan X
J Physiol
. 2023 Nov;
602(21):5745-5756.
PMID: 38031820
Acute respiratory distress syndrome (ARDS) is characterized by bilateral chest infiltration and acute hypoxic respiratory failure. ARDS carries significant morbidity and mortality despite advancements in medical management, calling for the...