Karen G N Oshiro
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Explore the profile of Karen G N Oshiro including associated specialties, affiliations and a list of published articles.
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16
Citations
322
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Recent Articles
1.
Rezende S, Chan L, Oshiro K, Buccini D, Leal A, Ribeiro C, et al.
Biochim Biophys Acta Gen Subj
. 2024 Aug;
1868(11):130693.
PMID: 39147109
Background: Resistant infectious diseases caused by gram-negative bacteria are among the most serious worldwide health problems. Antimicrobial peptides (AMPs) have been explored as promising antibacterial, antibiofilm, and anti-infective candidates to...
2.
Quigua-Orozco R, Andrade I, Oshiro K, Rezende S, Santos A, Pereira J, et al.
Chem Biol Drug Des
. 2024 Jul;
104(1):e14588.
PMID: 39048531
Diverse computational approaches have been widely used to assist in designing antimicrobial peptides with enhanced activities. This tactic has also been used to address the need for new treatment alternatives...
3.
Orozco R, Oshiro K, Pinto I, Buccini D, Almeida C, Nieto Marin V, et al.
J Bacteriol
. 2024 Apr;
206(5):e0007124.
PMID: 38629875
Bovine mastitis is a frequent infection in lactating cattle, causing great economic losses. represents the main etiological agent, which causes recurrent and persistent intramammary infections because conventional antibiotics are ineffective...
4.
Oshiro K, Freitas C, Rezende S, Orozco R, Chan L, Lawrence N, et al.
FEBS J
. 2023 Nov;
291(5):865-883.
PMID: 37997610
Mastoparans are cationic peptides with multifunctional pharmacological properties. Mastoparan-R1 and mastoparan-R4 were computationally designed based on native mastoparan-L from wasps and have improved therapeutic potential for the control of bacterial...
5.
Cardoso M, Chan L, Candido E, Buccini D, Rezende S, Torres M, et al.
Chem Sci
. 2022 Sep;
13(32):9410-9424.
PMID: 36093022
Structural diversity drives multiple biological activities and mechanisms of action in linear peptides. Here we describe an unusual N-capping asparagine-lysine-proline (NKP) motif that confers a hybrid multifunctional scaffold to a...
6.
Rezende S, Oshiro K, Junior N, Franco O, Cardoso M
Chem Commun (Camb)
. 2021 Oct;
57(88):11578-11590.
PMID: 34652348
Antimicrobial peptides (AMPs) are pinpointed as promising molecules against antibiotic-resistant bacterial infections. Nevertheless, there is a discrepancy between the AMP sequences generated and the tangible outcomes in clinical trials. AMPs'...
7.
Felicio M, Silveira G, Oshiro K, Meneguetti B, Franco O, Santos N, et al.
J Antimicrob Chemother
. 2021 Jan;
76(5):1174-1186.
PMID: 33501992
Objectives: The number of bacterial pathogens resistant to the currently available antibiotics has dramatically increased, with antimicrobial peptides (AMPs) being among the most promising potential new drugs. In this study,...
8.
Cardoso M, Orozco R, Rezende S, Rodrigues G, Oshiro K, Candido E, et al.
Front Microbiol
. 2020 Feb;
10:3097.
PMID: 32038544
Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely investigated as potential alternatives to antibiotic-based therapies. Indeed, naturally occurring and synthetic AMPs have shown promising results against a series of...
9.
Oshiro K, Rodrigues G, Monges B, Cardoso M, Franco O
Front Microbiol
. 2019 Nov;
10:2169.
PMID: 31681179
Infections caused by invasive fungal biofilms have been widely associated with high morbidity and mortality rates, mainly due to the advent of antibiotic resistance. Moreover, fungal biofilms impose an additional...
10.
Cardoso M, Meneguetti B, Costa B, Buccini D, Oshiro K, Preza S, et al.
Int J Mol Sci
. 2019 Oct;
20(19).
PMID: 31581426
The advent of multidrug resistance among pathogenic bacteria has attracted great attention worldwide. As a response to this growing challenge, diverse studies have focused on the development of novel anti-infective...