Cesar de la Fuente-Nunez
Overview
Explore the profile of Cesar de la Fuente-Nunez including associated specialties, affiliations and a list of published articles.
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Articles
156
Citations
4933
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Recent Articles
1.
Osiro K, Gil-Ley A, Fernandes F, de Oliveira K, de la Fuente-Nunez C, Franco O
Microb Cell
. 2025 Feb;
12:1-8.
PMID: 40012704
Molecular de-extinction has emerged as a novel strategy for studying biological molecules throughout evolutionary history. Among the myriad possibilities offered by ancient genomes and proteomes, antimicrobial peptides (AMPs) stand out...
2.
Torres M, Chen T, Wan F, Chatterjee P, de la Fuente-Nunez C
bioRxiv
. 2025 Feb;
PMID: 39975107
Generative artificial intelligence (AI) offers a powerful avenue for peptide design, yet this process remains challenging due to the vast sequence space, complex structure-activity relationships, and the need to balance...
3.
Guan C, Fernandes F, Franco O, de la Fuente-Nunez C
Cell Rep Phys Sci
. 2025 Feb;
6(1).
PMID: 39949833
Large language models (LLMs) have significantly impacted various domains of our society, including recent applications in complex fields such as biology and chemistry. These models, built on sophisticated neural network...
4.
Zhang X, de la Fuente-Nunez C, Wang J
Life Med
. 2025 Jan;
2(2):lnad005.
PMID: 39872113
No abstract available.
5.
Wan F, Wong F, Collins J, de la Fuente-Nunez C
Nat Rev Bioeng
. 2025 Jan;
2(5):392-407.
PMID: 39850516
Artificial intelligence (AI) and machine learning (ML) models are being deployed in many domains of society and have recently reached the field of drug discovery. Given the increasing prevalence of...
6.
Cesaro A, Hoffman S, Das P, de la Fuente-Nunez C
NPJ Antimicrob Resist
. 2025 Jan;
3(1):2.
PMID: 39843587
Artificial intelligence (AI) has transformed infectious disease control, enhancing rapid diagnosis and antibiotic discovery. While conventional tests delay diagnosis, AI-driven methods like machine learning and deep learning assist in pathogen...
7.
Candido E, Gasparetto L, Luchi L, Pimentel J, Cardoso M, Macedo M, et al.
ACS Infect Dis
. 2025 Jan;
11(2):386-397.
PMID: 39842000
Plants provide an abundant source of potential therapeutic agents, including a diverse array of compounds, such as cyclotides, which are peptides known for their antimicrobial activity. Cyclotides are multifaceted molecules...
8.
Guan C, Wan F, Torres M, de la Fuente-Nunez C
bioRxiv
. 2025 Jan;
PMID: 39829868
A variety of deep generative models have been adopted to perform functional protein generation. Compared to 3D protein design, sequence-based generation methods, which aim to generate amino acid sequences with...
9.
Galeota-Sprung B, Bhatt A, de la Fuente-Nunez C
Trends Genet
. 2025 Jan;
41(2):104-106.
PMID: 39809670
Recent advances in computational prediction and experimental techniques have detected previously unknown microproteins, particularly in the human microbiome. These small proteins, produced by diverse microbial species, are emerging as promising...
10.
Guan C, Torres M, Li S, de la Fuente-Nunez C
bioRxiv
. 2025 Jan;
PMID: 39764027
The relentless emergence of antibiotic-resistant pathogens, particularly Gram-negative bacteria, highlights the urgent need for novel therapeutic interventions. Drug-resistant infections account for approximately 5 million deaths annually, yet the antibiotic development...