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Karen G N Oshiro

Explore the profile of Karen G N Oshiro including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 322
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Recent Articles
11.
Oshiro K, Candido E, Chan L, Torres M, Monges B, Rodrigues S, et al.
J Med Chem . 2019 Aug; 62(17):8140-8151. PMID: 31411881
Diverse peptides have been evaluated for their activity against pathogenic microorganisms. Here, five mastoparan variants were designed based on mastoparan-L, among which two (R1 and R4) were selected for in-depth...
12.
Candido E, Cardoso M, Chan L, Torres M, Oshiro K, Porto W, et al.
ACS Infect Dis . 2019 Apr; 5(7):1081-1086. PMID: 31016969
Bacterial biofilms and associated infections represent one of the biggest challenges in the clinic, and as an alternative to counter bacterial infections, antimicrobial peptides have attracted great attention in the...
13.
Torres M, Pedron C, Higashikuni Y, Kramer R, Cardoso M, Oshiro K, et al.
Commun Biol . 2018 Dec; 1:221. PMID: 30534613
Antimicrobial peptides (AMPs) constitute promising alternatives to classical antibiotics for the treatment of drug-resistant infections, which are a rapidly emerging global health challenge. However, our understanding of the structure-function relationships...
14.
Cardoso M, Candido E, Chan L, Torres M, Oshiro K, Rezende S, et al.
ACS Infect Dis . 2018 Oct; 4(12):1727-1736. PMID: 30346140
Computer-aided screening of antimicrobial peptides (AMPs) is a promising approach for discovering novel therapies against multidrug-resistant bacterial infections. Here, we functionally and structurally characterized an Escherichia coli-derived AMP (EcDBS1R5) previously...
15.
Cardoso M, Oshiro K, Rezende S, Candido E, Franco O
Adv Protein Chem Struct Biol . 2018 Apr; 112:359-384. PMID: 29680241
Antimicrobial peptides (AMPs) have been widely isolated from most organisms in nature. This class of antimicrobials may undergo changes in their sequence for improved physicochemical properties, including charge, hydrophobicity, and...
16.
Meneguetti B, Machado L, Oshiro K, Nogueira M, Carvalho C, Franco O
Front Microbiol . 2017 Jan; 7:2136. PMID: 28119671
Bacterial resistance is a major threat to plant crops, animals and human health, and over the years this situation has increasingly spread worldwide. Due to their many bioactive compounds, plants...