Octavio L Franco
Overview
Explore the profile of Octavio L Franco including associated specialties, affiliations and a list of published articles.
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271
Citations
4049
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Recent Articles
1.
Osiro K, Gil-Ley A, Fernandes F, de Oliveira K, de la Fuente-Nunez C, Franco O
Microb Cell
. 2025 Feb;
12:1-8.
PMID: 40012704
Molecular de-extinction has emerged as a novel strategy for studying biological molecules throughout evolutionary history. Among the myriad possibilities offered by ancient genomes and proteomes, antimicrobial peptides (AMPs) stand out...
2.
Morales-Vicente F, Espinosa L, Diaz-Pico E, Martell E, Gonzalez M, Ojeda G, et al.
Antibiotics (Basel)
. 2025 Feb;
14(2).
PMID: 40001437
: Cm-p5 and its cyclic monomeric and dimeric analogues are known for their antifungal, antibacterial, antiviral, and antibiofilm activities. Previously, our cyclization method produced a mixture of peptides that were...
3.
Guan C, Fernandes F, Franco O, de la Fuente-Nunez C
Cell Rep Phys Sci
. 2025 Feb;
6(1).
PMID: 39949833
Large language models (LLMs) have significantly impacted various domains of our society, including recent applications in complex fields such as biology and chemistry. These models, built on sophisticated neural network...
4.
Ribeiro F, Arnaldo L, P Milhomem L, Passos L, S Aguiar S, Aguiar S, et al.
Peptides
. 2025 Feb;
185:171356.
PMID: 39929256
There are different molecular pathways that regulate appetite, particularly the role of the hypothalamus, circadian rhythms, and gastrointestinal peptides. The hypothalamus integrates signals from orexigenic peptides like neuropeptide Y (NPY)...
5.
Cardoso M, de Lima L, Pires A, Maximiano M, Harvey P, Freitas C, et al.
ACS Omega
. 2024 Nov;
9(45):45297-45308.
PMID: 39554447
Defensins are present in many organisms and are divided into two evolutionary groups, termed - and -defensins. -defensins have only recently been reported in bacteria, and knowledge of these defensins...
6.
Osiro K, Hashemi N, Brango-Vanegas J, Oliveira S, Franco O
Expert Opin Biol Ther
. 2024 Nov;
24(12):1311-1315.
PMID: 39548688
No abstract available.
7.
Rezende S, Chan L, Oshiro K, Buccini D, Leal A, Ribeiro C, et al.
Biochim Biophys Acta Gen Subj
. 2024 Aug;
1868(11):130693.
PMID: 39147109
Background: Resistant infectious diseases caused by gram-negative bacteria are among the most serious worldwide health problems. Antimicrobial peptides (AMPs) have been explored as promising antibacterial, antibiofilm, and anti-infective candidates to...
8.
Quigua-Orozco R, Andrade I, Oshiro K, Rezende S, Santos A, Pereira J, et al.
Chem Biol Drug Des
. 2024 Jul;
104(1):e14588.
PMID: 39048531
Diverse computational approaches have been widely used to assist in designing antimicrobial peptides with enhanced activities. This tactic has also been used to address the need for new treatment alternatives...
9.
Ribeiro F, Anderson M, Aguiar S, Gabriela E, Petriz B, Franco O
Nutr Res
. 2024 Jun;
127():27-39.
PMID: 38843565
Gut peptides play a role in signaling appetite control in the hypothalamus. Limited knowledge exists regarding the release of these peptides in individuals with obesity before and during external stimuli....
10.
Cardoso M, de la Fuente-Nunez C, Santos N, Zasloff M, Franco O
Trends Microbiol
. 2024 May;
32(7):624-627.
PMID: 38777700
Many factors contribute to bacterial membrane stabilization, including steric effects between lipids, membrane spontaneous curvature, and the difference in the number of neighboring molecules. This forum provides an overview of...