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Marlon H Cardoso

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Articles 44
Citations 515
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Recent Articles
1.
Cardoso M, de Lima L, Pires A, Maximiano M, Harvey P, Freitas C, et al.
ACS Omega . 2024 Nov; 9(45):45297-45308. PMID: 39554447
Defensins are present in many organisms and are divided into two evolutionary groups, termed - and -defensins. -defensins have only recently been reported in bacteria, and knowledge of these defensins...
2.
Rezende S, Chan L, Oshiro K, Buccini D, Leal A, Ribeiro C, et al.
Biochim Biophys Acta Gen Subj . 2024 Aug; 1868(11):130693. PMID: 39147109
Background: Resistant infectious diseases caused by gram-negative bacteria are among the most serious worldwide health problems. Antimicrobial peptides (AMPs) have been explored as promising antibacterial, antibiofilm, and anti-infective candidates to...
3.
Quigua-Orozco R, Andrade I, Oshiro K, Rezende S, Santos A, Pereira J, et al.
Chem Biol Drug Des . 2024 Jul; 104(1):e14588. PMID: 39048531
Diverse computational approaches have been widely used to assist in designing antimicrobial peptides with enhanced activities. This tactic has also been used to address the need for new treatment alternatives...
4.
Brango-Vanegas J, Leite M, Macedo M, Cardoso M, Franco O
Front Chem . 2024 Jun; 12:1382954. PMID: 38873409
N-capping (N-cap) and C-capping (C-cap) in biologically active peptides, including specific amino acids or unconventional group motifs, have been shown to modulate activity against pharmacological targets by interfering with the...
5.
Cardoso M, de la Fuente-Nunez C, Santos N, Zasloff M, Franco O
Trends Microbiol . 2024 May; 32(7):624-627. PMID: 38777700
Many factors contribute to bacterial membrane stabilization, including steric effects between lipids, membrane spontaneous curvature, and the difference in the number of neighboring molecules. This forum provides an overview of...
6.
Orozco R, Oshiro K, Pinto I, Buccini D, Almeida C, Nieto Marin V, et al.
J Bacteriol . 2024 Apr; 206(5):e0007124. PMID: 38629875
Bovine mastitis is a frequent infection in lactating cattle, causing great economic losses. represents the main etiological agent, which causes recurrent and persistent intramammary infections because conventional antibiotics are ineffective...
7.
Angeles-Boza A, Santos N, Cardoso M
Front Microbiol . 2023 Nov; 14:1304997. PMID: 38029136
No abstract available.
8.
Oshiro K, Freitas C, Rezende S, Orozco R, Chan L, Lawrence N, et al.
FEBS J . 2023 Nov; 291(5):865-883. PMID: 37997610
Mastoparans are cationic peptides with multifunctional pharmacological properties. Mastoparan-R1 and mastoparan-R4 were computationally designed based on native mastoparan-L from wasps and have improved therapeutic potential for the control of bacterial...
9.
Fleitas O, Fontes W, De Souza C, Da Costa M, Cardoso M, Castro M, et al.
J Antimicrob Chemother . 2023 Nov; 79(1):112-122. PMID: 37966053
Background: The synthetic antimicrobial peptide, PaDBS1R1, has been reported as a powerful anti-Klebsiella pneumoniae antimicrobial. However, there is only scarce knowledge about whether K. pneumoniae could develop resistance against PaDBS1R1...
10.
Fernandes F, Cardoso M, Gil-Ley A, Luchi L, da Silva M, Macedo M, et al.
Front Bioinform . 2023 Jul; 3:1216362. PMID: 37521317
Antimicrobial peptides (AMPs) are components of natural immunity against invading pathogens. They are polymers that fold into a variety of three-dimensional structures, enabling their function, with an underlying sequence that...