Graham T Dempsey
Overview
Explore the profile of Graham T Dempsey including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
1826
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
McManus O, Werley C, Dempsey G
J Gen Physiol
. 2019 Mar;
151(6):714-717.
PMID: 30902836
No abstract available.
12.
Williams L, Joshi V, Murphy M, Ferrante J, Werley C, Brookings T, et al.
Neurochem Res
. 2019 Jan;
44(3):714-725.
PMID: 30603979
Induced pluripotent stem (iPS) cells offer the exciting opportunity for modeling neurological disorders in vitro in the context of a human genetic background. While significant progress has been made in...
13.
Werley C, Brookings T, Upadhyay H, Williams L, McManus O, Dempsey G
Curr Protoc Pharmacol
. 2017 Sep;
78:11.20.1-11.20.24.
PMID: 28892145
A key challenge for establishing a phenotypic screen for neuronal excitability is measurement of membrane potential changes with high throughput and accuracy. Most approaches for probing excitability rely on low-throughput,...
14.
Hempel C, Werley C, Dempsey G, Gerber D
Drug Discov Today Technol
. 2017 Jun;
23:17-25.
PMID: 28647082
There is a pressing need for new and more effective treatments for central nervous system (CNS) disorders. A large body of evidence now suggests that alterations in synaptic transmission and...
15.
Dempsey G, Chaudhary K, Atwater N, Nguyen C, Brown B, McNeish J, et al.
J Pharmacol Toxicol Methods
. 2016 May;
81:240-50.
PMID: 27184445
Introduction: The Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative seeks an in vitro test to accurately predict clinical Torsades de Pointes (TdP). We developed a cardiotoxicity assay incorporating simultaneous measurement...
16.
Wang S, Moffitt J, Dempsey G, Xie X, Zhuang X
Proc Natl Acad Sci U S A
. 2014 Jun;
111(23):8452-7.
PMID: 24912163
Photoactivatable fluorescent proteins (PAFPs) have been widely used for superresolution imaging based on the switching and localization of single molecules. Several properties of PAFPs strongly influence the quality of the...
17.
Dempsey G
Methods Cell Biol
. 2013 Aug;
114:561-92.
PMID: 23931523
Advances in far-field fluorescence microscopy over the past decade have led to the development of super-resolution imaging techniques that provide more than an order of magnitude improvement in spatial resolution...
18.
Vaughan J, Dempsey G, Sun E, Zhuang X
J Am Chem Soc
. 2013 Jan;
135(4):1197-200.
PMID: 23311875
We report that the cyanine dye Cy5 and several of its structural relatives are reversibly quenched by the phosphine tris(2-carboxyethyl)phosphine (TCEP). Using Cy5 as a model, we show that the...
19.
Berk V, Fong J, Dempsey G, Develioglu O, Zhuang X, Liphardt J, et al.
Science
. 2012 Jul;
337(6091):236-9.
PMID: 22798614
In their natural environment, microbes organize into communities held together by an extracellular matrix composed of polysaccharides and proteins. We developed an in vivo labeling strategy to allow the extracellular...
20.
Bates M, Dempsey G, Chen K, Zhuang X
Chemphyschem
. 2012 Jan;
13(1):99-107.
PMID: 22213647
Understanding the complexity of the cellular environment will benefit from the ability to unambiguously resolve multiple cellular components, simultaneously and with nanometer-scale spatial resolution. Multicolor super-resolution fluorescence microscopy techniques have...