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Trends in Pharmacological Sciences

Trends in Pharmacological Sciences is a leading scientific journal that publishes cutting-edge research and reviews in the field of pharmacology. It covers a wide range of topics including drug discovery, mechanisms of action, therapeutic applications, and emerging trends in pharmacology. With its authoritative content and global reach, this journal serves as a valuable resource for researchers, clinicians, and pharmaceutical professionals seeking to stay updated on the latest advancements in pharmacological sciences.

Details
Abbr. Trends Pharmacol Sci
Start 1979
End Continuing
Frequency Monthly
p-ISSN 0165-6147
e-ISSN 1873-3735
Country United Kingdom
Language English
Specialty Pharmacology
Metrics
h-index / Ranks: 400 244
SJR / Ranks: 526 3232
CiteScore / Ranks: 252 23.30
JIF / Ranks: 255 13.8
Recent Articles
1.
Shen Y, Zhang H, Xue M, Zheng C, Chen Q
Trends Pharmacol Sci . 2025 Mar; PMID: 40069043
Herpes simplex virus type 1 (HSV-1) is a DNA virus with strong replication capabilities, a large genomic payload (≥30 kb), and low toxicity, making it a prominent vector in cancer...
2.
Schmidt B, De Logu F, Nassini R, Geppetti P, Bunnett N
Trends Pharmacol Sci . 2025 Mar; PMID: 40057436
Chronic pain is common and debilitating, yet is inadequately treated by current therapies, which can have life-threatening side effects. Treatments targeting G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs),...
3.
Guesdon A, Bourguet W
Trends Pharmacol Sci . 2025 Mar; PMID: 40057435
The aryl hydrocarbon receptor (AHR) is a crucial chemosensory protein and an emerging therapeutic target. However, the lack of structural data has long hindered a complete understanding of the mechanisms...
4.
van Gool R, Al-Hertani W, Bodamer O, Upadhyay J
Trends Pharmacol Sci . 2025 Mar; PMID: 40055076
No abstract available.
5.
Howard G, Tansey W
Trends Pharmacol Sci . 2025 Mar; PMID: 40044536
Ribosomes and ribosome biogenesis (RiBi) are universally corrupted in cancer, fueling the high rates of translation that sustain malignancy and creating opportunities for discriminating therapeutic intervention. Despite longstanding recognition of...
6.
Kalyanaraman H, Pal China S, Casteel D, Pilz R
Trends Pharmacol Sci . 2025 Feb; 46(3):279-294. PMID: 40011087
Testosterone, the primary androgen in males, is required for optimal bone mass and strength in men, but the benefits of testosterone therapy in elderly men with modestly reduced testosterone levels...
7.
Song Y, Yu B
Trends Pharmacol Sci . 2025 Feb; 46(3):204-219. PMID: 39966067
Lysine-specific demethylase 1 (LSD1) is a key enzyme that removes the methylation marks from lysines in the histone tails of nucleosomes. Emerging evidence suggests that LSD1 exhibits both enzyme-dependent and...
8.
Lehmann L, Gross V, Behlendorf R, Promel S
Trends Pharmacol Sci . 2025 Feb; 46(3):231-248. PMID: 39955242
Adhesion G-protein-coupled receptors (aGPCRs) play key roles in health and disease. They are unique in that they not only activate G-protein pathways but also have distinct functions that rely solely...
9.
Wischnewski S, Rausch H, Ikenaga C, Leipe J, Lloyd T, Schirmer L
Trends Pharmacol Sci . 2025 Feb; 46(3):249-263. PMID: 39939222
Idiopathic inflammatory myopathies (IIMs), or myositis, are rare diseases marked by immune-driven muscle damage and complications like skin lesions and interstitial lung disease (ILD). Despite advances, challenges in diagnosis and...
10.
Neil C, Schaening-Burgos C, Alexis M, Reynolds D, Smith P, Seiler M, et al.
Trends Pharmacol Sci . 2025 Feb; 46(3):264-278. PMID: 39915130
Poison exons (PEs) are a class of alternatively spliced exons whose inclusion targets mRNA transcripts for degradation via the nonsense-mediated decay (NMD) pathway. Although a role for NMD as an...