Steven J Ryan
Overview
Explore the profile of Steven J Ryan including associated specialties, affiliations and a list of published articles.
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11
Citations
269
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Recent Articles
1.
Fink J, Delaney-Busch N, Dawes R, Nanou E, Folts C, Harikrishnan K, et al.
Commun Biol
. 2024 Nov;
7(1):1447.
PMID: 39506078
Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by hypermethylation of expanded CGG repeats (>200) in the FMR1 gene leading to gene silencing and loss of Fragile X Messenger...
2.
Liu P, Zhang H, Werley C, Pichler M, Ryan S, Lewarch C, et al.
Pain
. 2023 Nov;
165(4):922-940.
PMID: 37963235
Chronic pain associated with osteoarthritis (OA) remains an intractable problem with few effective treatment options. New approaches are needed to model the disease biology and to drive discovery of therapeutics....
3.
Williams L, Gerber D, Elder A, Tseng W, Baru V, Delaney-Busch N, et al.
Mol Ther Nucleic Acids
. 2022 Jul;
29:189-203.
PMID: 35860385
Mutations in the gene are the cause of an ultra-rare neurological disorder characterized by intellectual disability, impaired speech, motor delay, and hypotonia evolving to spasticity, central sleep apnea, and premature...
4.
Simkin D, Papakis V, Bustos B, Ambrosi C, Ryan S, Baru V, et al.
Stem Cell Reports
. 2022 Mar;
17(4):993-1008.
PMID: 35276091
The ability to precisely edit the genome of human induced pluripotent stem cell (iPSC) lines using CRISPR/Cas9 has enabled the development of cellular models that can address genotype to phenotype...
5.
Daniel S, Menigoz A, Guo J, Ryan S, Seth S, Rainnie D
Neuropharmacology
. 2019 Mar;
150:80-90.
PMID: 30878403
Distinct regions and cell types in the anterolateral group of the bed nucleus of the stria terminalis (BNST) act to modulate anxiety in opposing ways. A history of chronic stress...
6.
Amadei E, Johnson Z, Kwon Y, Shpiner A, Saravanan V, Mays W, et al.
Nature
. 2017 Jun;
546(7657):297-301.
PMID: 28562592
Adult pair bonding involves dramatic changes in the perception and valuation of another individual. One key change is that partners come to reliably activate the brain's reward system, although the...
7.
Ehrlich D, Neigh G, Bourke C, Nemeth C, Hazra R, Ryan S, et al.
Neuropharmacology
. 2015 Jun;
97:251-8.
PMID: 26032436
Depression during pregnancy has been linked to in utero stress and is associated with long-lasting symptoms in offspring, including anxiety, helplessness, attentional deficits, and social withdrawal. Depression is diagnosed in...
8.
Ryan S, Ehrlich D, Rainnie D
Brain Struct Funct
. 2014 Nov;
221(2):839-54.
PMID: 25381464
The basolateral nucleus of the amygdala (BLA) assigns emotional valence to sensory stimuli, and many amygdala-dependent behaviors undergo marked development during postnatal life. We recently showed principal neurons in the...
9.
Ehrlich D, Ryan S, Hazra R, Guo J, Rainnie D
J Neurophysiol
. 2013 May;
110(4):926-41.
PMID: 23719209
Many psychiatric disorders, including anxiety and autism spectrum disorders, have early ages of onset and high incidence in juveniles. To better treat and prevent these disorders, it is important to...
10.
Ryan S, Ehrlich D, Jasnow A, Daftary S, Madsen T, Rainnie D
PLoS One
. 2012 May;
7(4):e35320.
PMID: 22563382
The basolateral complex of the amygdala (BLA) is a critical component of the neural circuit regulating fear learning. During fear learning and recall, the amygdala and other brain regions, including...