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Alan H Shih

Explore the profile of Alan H Shih including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 2790
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31.
Abdel-Wahab O, Adli M, LaFave L, Gao J, Hricik T, Shih A, et al.
Cancer Cell . 2012 Aug; 22(2):180-93. PMID: 22897849
Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome, myeloproliferative neoplasms, and acute myeloid leukemia, and are associated with adverse outcome. Despite the genetic and clinical data implicating ASXL1...
32.
Shih A, Levine R
Semin Oncol . 2011 Sep; 38(5):613-20. PMID: 21943667
Myelodysplastic syndromes (MDS) are a group of clonal hematopoetic disorders marked by ineffective hematopoiesis, peripheral cytopenias, and an increased risk of transformation to acute myeloid leukemia. Multiple processes govern hematopoietic...
33.
Shih A, Holland E
Neoplasia . 2007 Jan; 8(12):1072-82. PMID: 17217625
Recent findings suggest that Notch signaling is active in brain tumors and stem cells, and that stem cells or cells with progenitor characteristics contribute to brain tumor formation. These stem...
34.
Lassman A, Rossi M, Raizer J, Razier J, Abrey L, Lieberman F, et al.
Clin Cancer Res . 2005 Nov; 11(21):7841-50. PMID: 16278407
Purpose: We investigated the molecular effect of the epidermal growth factor receptor (EGFR) inhibitors erlotinib and gefitinib in vivo on all available tumors from patients treated on North American Brain...
35.
Shih A, Holland E
Cancer Lett . 2005 Sep; 232(2):139-47. PMID: 16139423
Platelet-derived growth factor (PDGF) has long been implicated in cancer and is known to be involved in many biological processes. In Central Nervous System (CNS) neoplasms, particularly gliomas, PDGF is...
36.
Shih A, Holland E
J Neurooncol . 2005 Jan; 70(2):125-36. PMID: 15674474
Our knowledge of the causes of brain tumors has steadily increased and is leading to a refined understanding of the signaling pathways that may be essential for tumor formation. At...
37.
Shih A, Dai C, Hu X, Rosenblum M, Koutcher J, Holland E
Cancer Res . 2004 Jul; 64(14):4783-9. PMID: 15256447
Platelet-derived growth factor (PDGF) is expressed in many different tumors, but its precise roles in tumorigenesis remain to be fully defined. Here, we report on a mouse model that demonstrates...