Craig B Thompson
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Explore the profile of Craig B Thompson including associated specialties, affiliations and a list of published articles.
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246
Citations
66090
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Recent Articles
1.
Naghdi S, Mishra P, Roy S, Weaver D, Walter L, Davies E, et al.
Nat Commun
. 2025 Mar;
16(1):2416.
PMID: 40069152
Differences between normal tissues and invading tumors that allow tumor targeting while saving normal tissue are much sought after. Here we show that scarcity of VDAC2, and the consequent lack...
2.
Fu Y, Land M, Kavlashvili T, Cui R, Kim M, DeBitetto E, et al.
Cell
. 2025 Mar;
PMID: 40068680
Recent breakthroughs in the genetic manipulation of mitochondrial DNA (mtDNA) have enabled precise base substitutions and the efficient elimination of genomes carrying pathogenic mutations. However, reconstituting mtDNA deletions linked to...
3.
Schild T, Wallisch P, Zhao Y, Wang Y, Haughton L, Chirayil R, et al.
Cancer Cell
. 2025 Feb;
43(3):552-562.e9.
PMID: 40020672
Fructose consumption is elevated in western diets, but its impact on anti-tumor immunity is unclear. Fructose is metabolized in the liver and small intestine, where fructose transporters are highly expressed....
4.
Fung T, Ryu K, Thompson C
EMBO J
. 2025 Feb;
44(5):1275-1293.
PMID: 39920310
L-arginine is the most nitrogen-rich amino acid, acting as a key precursor for the synthesis of nitrogen-containing metabolites and an essential intermediate in the clearance of excess nitrogen. Arginine's side...
5.
Ryu K, Fung T, Baker D, Saoi M, Park J, Febres-Aldana C, et al.
Nature
. 2024 Nov;
635(8039):746-754.
PMID: 39506109
Mitochondria serve a crucial role in cell growth and proliferation by supporting both ATP synthesis and the production of macromolecular precursors. Whereas oxidative phosphorylation (OXPHOS) depends mainly on the oxidation...
6.
Fu Y, Land M, Cui R, Kavlashvili T, Kim M, Lieber T, et al.
bioRxiv
. 2024 Oct;
PMID: 39463974
Highlights: Combining prokaryotic end-joining with targeted endonucleases generates specific mtDNA deletions in human cellsEngineering a panel of cell lines with a large-scale deletion that spans the full spectrum of heteroplasmy75%...
7.
Pavlova N, Thompson C
Cold Spring Harb Perspect Med
. 2024 Apr;
14(10).
PMID: 38565265
A cell committed to proliferation must reshape its metabolism to enable robust yet balanced production of building blocks for the assembly of proteins, lipids, nucleic acids, and other macromolecules, from...
8.
Thompson C, Vousden K, Johnson R, Koppenol W, Sies H, Lu Z, et al.
Nat Metab
. 2023 Nov;
5(11):1840-1843.
PMID: 37990075
No abstract available.
9.
Cai X, Ng C, Jones O, Fung T, Ryu K, Li D, et al.
Mol Cell
. 2023 Oct;
83(21):3904-3920.e7.
PMID: 37879334
Lactate has long been considered a cellular waste product. However, we found that as extracellular lactate accumulates, it also enters the mitochondrial matrix and stimulates mitochondrial electron transport chain (ETC)...
10.
Cai X, Ng C, Jones O, Fung T, Ryu K, Li D, et al.
bioRxiv
. 2023 Aug;
PMID: 37577602
Lactate has long been considered a cellular waste product. However, we found that as extracellular lactate accumulates, it also enters the mitochondrial matrix and stimulates mitochondrial electron transport chain (ETC)...