Cancer Letters
Overview
Cancer Letters is a renowned peer-reviewed journal dedicated to advancing cancer research and treatment. It publishes cutting-edge studies on various aspects of cancer biology, including molecular mechanisms, tumor progression, therapeutic interventions, and clinical trials. With a multidisciplinary approach, Cancer Letters serves as a valuable resource for scientists, clinicians, and researchers seeking to deepen their understanding of cancer and develop novel strategies for its prevention and management.
Details
Details
Metrics
Metrics
h-index / Ranks: 570
216
SJR / Ranks: 782
2595
CiteScore / Ranks: 510
16.70
JIF / Ranks: 485
9.7
Recent Articles
1.
Hossain S, Gimenez G, Stockwell P, Weeks R, Almomani S, Jones G, et al.
Cancer Lett
. 2025 Mar;
:217638.
PMID: 40089202
Successful immune checkpoint inhibitor (ICI) therapy occurs in only a fraction of melanoma patients, and yet all patients are susceptible to potentially serious ICI-related side-effects. No current biomarkers robustly predict...
2.
Xiong S, Zhang Y, Zhou X, Pant V, Mirani A, Gencel-Augusto J, et al.
Cancer Lett
. 2025 Mar;
:217622.
PMID: 40081463
Both Mdm2 and Mdm4 inhibit p53 activity by masking of its transcriptional activation domain. In addition, Mdm2 functions as an E3 ubiquitin ligase, targeting p53 for degradation. The Mdm4 amino...
3.
Wang Q, Sun Z, Guo J, Li H, Zhang J, Zhang B, et al.
Cancer Lett
. 2025 Mar;
:217596.
PMID: 40081462
M2 macrophages play a critical role in the tumor microenvironment of invasive solid tumors. They are closely associated with perineural invasion (PNI) and are often linked to poor prognosis. In...
4.
Wang Z, He K, Liu M, Lv W, Cheng B, Zhang G, et al.
Cancer Lett
. 2025 Mar;
:217623.
PMID: 40074070
Mitochondrial malfunction is traditionally viewed as a major factor in tumor growth and malignancy, while recent studies have introduced conflicting views suggesting the necessity of functional mitochondria for tumor growth....
5.
Xu L, Dai B, Zhang L, Chen W, Rong S, Chen J, et al.
Cancer Lett
. 2025 Mar;
617:217624.
PMID: 40074069
Follicular thyroid carcinoma (FTC) poses significant clinical challenges due to its vascular invasion tendency and distant metastasis potential, leading to poorer patient outcomes compared to other thyroid carcinomas. Although ubiquitin-conjugating...
6.
Geng Y, Chen Z, Luo T, Liu Y, Kong S, Yan X, et al.
Cancer Lett
. 2025 Mar;
:217619.
PMID: 40074068
The biliary system is crucial for liver function, regulating bile production, secretion, and transport. Dysfunctions within this system can lead to various diseases, such as cholangiopathies and biliary fibrosis, which...
7.
Pragasam A, Maurya S, Jain K, Pal S, Raja C, Yadav R, et al.
Cancer Lett
. 2025 Mar;
:217621.
PMID: 40074067
Gallbladder stones alone do not explain the risk of gallbladder cancer (GBC) as the sole etiological factor. Chronic microbial infection, particularly Salmonella, has been implicated in GB carcinogenesis, but its...
8.
Wu Z, Shan Q, Jiang Y, Huang W, Wang Z, Zhuang Y, et al.
Cancer Lett
. 2025 Mar;
617:217620.
PMID: 40068706
Pancreatic ductal adenocarcinoma (PDAC) is a "cold" solid tumor with frequent Major Histocompatibility Complex I (MHC-I) deficiency, thereby making it resistant to type-1-conventional dendritic cell (cDC1)-CD8T cell mediated anti-tumor immunity....
9.
Liu C, Xia S, Wang B, Li J, Wang X, Ren Y, et al.
Cancer Lett
. 2025 Mar;
617:217618.
PMID: 40058726
Osteopontin (OPN) is a multifunctional secretory protein which can be expressed and secreted by a variety of tumor cells and immune cells. Tumor microenvironment remodeling provides favorable conditions for tumor...
10.
Zhou X, Zhang N, Zhang X, Sun X, Ruan Z, Yang Q, et al.
Cancer Lett
. 2025 Mar;
617:217615.
PMID: 40056967
The cGAS-MITA/STING pathway plays critical roles in both host defense against DNA virus and intrinsic antitumor immunity by sensing viral genomic DNA or dis-located mitochondrial/cellular DNA. Whether carcinogenic metabolites can...