Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Overview
Clinical Cancer Research is the official journal of the American Association for Cancer Research. It publishes cutting-edge research on all aspects of cancer, including prevention, diagnosis, treatment, and survivorship. With a focus on clinical trials and translational research, this journal provides valuable insights into the latest advancements in cancer care and serves as a vital resource for oncologists, researchers, and healthcare professionals.
Details
Details
Abbr.
Clin Cancer Res
Start
1995
End
Continuing
Frequency
Semimonthly, Aug. 15, 2003-
p-ISSN
1078-0432
e-ISSN
1557-3265
Country
United States
Language
English
Specialty
Oncology
Metrics
Metrics
h-index / Ranks: 93
377
SJR / Ranks: 301
4623
CiteScore / Ranks: 291
21.80
JIF / Ranks: 354
11.5
Recent Articles
1.
Yin Y, Xu H, He L, Brown J, Mato A, Aittokallio T, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40085050
Purpose: The management of chronic lymphocytic leukemia (CLL) has significantly improved with targeted therapies. However, many patients experience a suboptimal response. To optimally select the best therapy, predictive biomarkers are...
2.
Fu H, Huang J, Zhao L, Chen Y, Xu W, Cai J, et al.
Clin Cancer Res
. 2025 Mar;
:OF1-OF12.
PMID: 40084923
Purpose: Fibroblast activation protein (FAP) is highly expressed in cancer-associated fibroblasts and certain tumor cells, making it a promising therapeutic target for various malignancies. This study evaluated the efficacy and...
3.
McCoon P, Wang Y, Lai Z, Zhang Q, Li W, Wildsmith S, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40080442
Purpose: Understanding the mutational landscape of recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) is important in identifying biomarkers to determine which patients may benefit from immune checkpoint inhibitors...
4.
Achatz M, Villani A, Bertuch A, Bougeard G, Chang V, Doria A, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40072304
Li-Fraumeni syndrome (LFS) is an autosomal dominant cancer predisposition condition characterized by a high lifetime risk for a wide spectrum of malignancies associated with germline pathogenic/likely pathogenic (P/LP) variants in...
5.
Lee J, Shin Y, Kwak J, Park H, Lee S, Kim M, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40072295
Purpose: Traditional methods, fine-needle aspiration cytology (FNAC) and washout thyroglobulin (Tg), do not always provide sufficient accuracy for diagnosing lymph node (LN) metastasis in thyroid cancer. This study aimed to...
6.
Guller U, Hayoz S, Horber D, Jochum W, De Dosso S, Koeberle D, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40067142
Purpose: We assessed the benefit of adjuvant aspirin in resected PIK3CA-mutated colon cancer patients. Patients & Methods: This was a phase III, prospective, randomized, placebo-controlled, double-blind, multicenter, and multinational trial....
7.
Kushner B, Modak S, Mauguen A, Basu E, Kramer K, Roberts S, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40067131
Purpose: Naxitamab is a humanized form of the murine anti-GD2 monoclonal antibody (mAb) 3F8. In an international trial, naxitamab+GM-CSF was effective against chemo-resistant high-risk neuroblastoma (HR-NB), leading to approval by...
8.
Zhang L, Teng P, Cavassani K, Wang J, Grasso C, Watson J, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40063516
Background: Circulating tumor cells (CTCs) with a very-small-nuclear phenotype (vsnCTCs) in prostate cancer (PCa) are characterized by nuclei smaller than 8.5 μm. Our previous studies established an association between vsnCTCs...
9.
Mitchell D, Brewster K, Makri S, Khan J, Albright E, Horvai A, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40063513
Purpose: MPNST is the leading cause of premature death among individuals with NF1 and the transcriptional aberrations that precede malignant transformation and contribute to MPNST tumorigenesis remain poorly defined. Alterations...
10.
Pereira R, Mackay A, Grabovska Y, Bradley A, Bloom T, Nicoll J, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40063504
Background: High-grade gliomas (HGG) occur in any central nervous system (CNS) location and any age. HGGs in teenagers/young adults (TYA) are understudied. This project aimed to characterise these tumours to...