Alpha 2.0
Login Register
» Articles » PMID: 1100764

Antigen-specific T-cell Factor in Cell Cooperation. Mapping Within the I Region of the H-2 Complex and Ability to Cooperate Across Allogeneic Barriers

Overview
Journal J Exp Med
Specialties Allergy & Immunology
General Medicine
Date 1975 Sep 1
PMID 1100764
Citations 50
Authors
M J Taussig
A J Munro
R Campbell
C S David
N A Staines
Affiliations
Soon will be listed here.
Abstract

Further mapping of the mouse T-cell factor specific for poly(Try,Glu)-polyD-LAla--polyLys is reported. It is shown to be a product of the I-A subregion of the H-2 complex by the use of antisera either raised specifically against or made specific, by absorption, for different regions of the H-2 complex. The factor cooperates across allogeneic barriers, e.g., when factor produced by one strian is combined with bone marrow cells of other H-2 incompatible strains.

Citing Articles

Concanavalin A-inducible, interleukin-2-producing T cell hybridoma.

Harwell L, Skidmore B, Marrack P, Kappler J J Exp Med. 1980; 152(4):893-904.

PMID: 6968339 PMC: 2185978. DOI: 10.1084/jem.152.4.893.

Non-H-2 restriction of expression of passively transferred delayed sensitivity.

Berche P, NORTH R J Exp Med. 1982; 155(5):1334-43.

PMID: 6802925 PMC: 2186690. DOI: 10.1084/jem.155.5.1334.

Helper and suppressor T cell factors.

Germain R, Benacerraf B Springer Semin Immunopathol. 1980; 3(1):93-127.

PMID: 6792727 DOI: 10.1007/BF00199927.

The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.

Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P J Exp Med. 1983; 157(4):1149-69.

PMID: 6601175 PMC: 2186983. DOI: 10.1084/jem.157.4.1149.

Regulation of the human allogeneic proliferative response in vitro.

Carosella E, Bensussan A, Lepage V, Sasportes M Immunogenetics. 1981; 14(1-2):107-16.

PMID: 6459995 DOI: 10.1007/BF00344304.

References
1.
Sela M . Antigen design and immune response. Harvey Lect. 1973; 67:213-46. View
2.
Shreffler D, David C . The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization. Adv Immunol. 1975; 20:125-95. DOI: 10.1016/s0065-2776(08)60208-4. View
3.
Katz D, Graves M, Dorf M, Dimuzio H, Benacerraf B . Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex. J Exp Med. 1975; 141(1):263-8. PMC: 2190506. DOI: 10.1084/jem.141.1.263. View
4.
Taussig M . T cell factor which can replace T cells in vivo. Nature. 1974; 248(445):234-6. DOI: 10.1038/248234a0. View
5.
Mozes E, Isac R, Taussig M . Antigen-specific T-cell factors in the genetic control of the immune response to poly(Tyr,Glu)-polyDLAla--polyLys. Evidence for T- and B-cell defects in SJL mice. J Exp Med. 1975; 141(3):703-7. PMC: 2189705. DOI: 10.1084/jem.141.3.703. View