Yang-Yang Ding
Overview
Explore the profile of Yang-Yang Ding including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
549
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0
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Recent Articles
1.
Ding Y, Sussman J, Madden K, Loftus J, Chen R, Falkenstein C, et al.
Blood
. 2025 Jan;
145(11):1195-1210.
PMID: 39774844
Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (Ph-like ALL) is driven by genetic alterations that induce constitutive kinase signaling and is associated with chemoresistance and high relapse risk in children and...
2.
Xu J, Chen C, Sussman J, Yoshimura S, Vincent T, Polonen P, et al.
Nat Cancer
. 2024 Nov;
6(1):102-122.
PMID: 39587259
Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to curing T cell acute lymphoblastic leukemia (T-ALL). While tumor heterogeneity has been implicated in treatment failure, the...
3.
Du L, Gao X, Ren X, Yang Y, Ding Y, Xu A, et al.
Acta Pharmacol Sin
. 2024 Sep;
46(2):366-379.
PMID: 39284878
Chronic itch is a maladaptive and debilitating symptom in patients with allergic contact dermatitis (ACD), adversely affecting their quality of life. There is a lack of effective treatments for ACD-associated...
4.
Pu L, Zheng H, Feng X, Charwudzi A, Liang X, Hu L, et al.
J Transl Med
. 2024 Jul;
22(1):613.
PMID: 38956649
Background: CD19-targeted chimeric antigen receptor T (CAR-T) cell therapy stands out as a revolutionary intervention, exhibiting remarkable remission rates in patients with refractory/relapsed (R/R) B-cell malignancies. However, the potential side...
5.
Zhang J, Zhou H, Zhu Z, Ding Y, He Y, Wei X, et al.
Biochem Biophys Res Commun
. 2024 Jun;
725:150272.
PMID: 38901224
Ketamine, an N-methyl-d-aspartate (NMDA) receptor antagonist, induces deficits in cognition and information processing following chronic abuse. Adolescent ketamine misuse represents a significant global public health issue; however, the neurodevelopmental mechanisms...
6.
Pu L, Li M, Feng X, Zhang T, Hu L, Zheng H, et al.
J Leukoc Biol
. 2024 Feb;
115(6):1094-1107.
PMID: 38369808
Myeloid-derived suppressor cells (MDSCs) are implicated in the regulation of immune responses closely associated with poor clinical outcomes in cancer. However, the MDSC subtypes in non-Hodgkin's lymphoma (NHL) have not...
7.
Tan K, Xu J, Chen C, Vincent T, Polonen P, Hu J, et al.
Res Sq
. 2023 Nov;
PMID: 37961674
Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to cure in T-cell Acute Lymphoblastic Leukemia (T-ALL). Biomarker guided risk stratification and targeted therapy have the potential...
8.
Chen C, Yu W, Alikarami F, Qiu Q, Chen C, Flournoy J, et al.
Blood
. 2021 Dec;
139(14):2198-2211.
PMID: 34864916
KMT2A-rearranged (KMT2A-r) infant acute lymphoblastic leukemia (ALL) is a devastating malignancy with a dismal outcome, and younger age at diagnosis is associated with increased risk of relapse. To discover age-specific...
9.
Ding Y, Kim H, Madden K, Loftus J, Chen G, Allen D, et al.
Clin Cancer Res
. 2021 Jul;
27(18):5109-5122.
PMID: 34210682
Purpose: Systems biology approaches can identify critical targets in complex cancer signaling networks to inform new therapy combinations that may overcome conventional treatment resistance. Experimental Design: We performed integrated analysis...
10.
Chen G, Chen C, Das R, Gao P, Chen C, Bandyopadhyay S, et al.
Cancer Discov
. 2021 Apr;
11(9):2186-2199.
PMID: 33820778
The adoptive transfer of chimeric antigen receptor (CAR) T cells represents a breakthrough in clinical oncology, yet both between- and within-patient differences in autologously derived T cells are a major...