Yang-Yang Ding
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Explore the profile of Yang-Yang Ding including associated specialties, affiliations and a list of published articles.
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21
Citations
549
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Recent Articles
11.
He B, Gao P, Ding Y, Chen C, Chen G, Chen C, et al.
Sci Adv
. 2020 Aug;
6(30):eaba3064.
PMID: 32832663
Interpreting the function of noncoding mutations in cancer genomes remains a major challenge. Here, we developed a computational framework to identify putative causal noncoding mutations of all classes by joint...
12.
Ding Y, Ramakrishna S, Long A, Phillips C, Montiel-Esparza R, Diorio C, et al.
Pediatr Blood Cancer
. 2020 Jun;
67(9):e28427.
PMID: 32588960
No abstract available.
13.
Chen G, Azzam A, Ding Y, Barrett D, Grupp S, Tan K
Clin Cancer Res
. 2020 Mar;
26(14):3505-3513.
PMID: 32127393
The adoptive transfer of genetically engineered chimeric antigen receptor (CAR) T cells has opened a new frontier in cancer therapy. Unlike the paradigm of targeted therapies, the efficacy of CAR...
14.
Hu Y, Chen C, Ding Y, Wen X, Wang B, Gao L, et al.
Nat Commun
. 2019 May;
10(1):2180.
PMID: 31097707
Most combination therapies are developed based on targets of existing drugs, which only represent a small portion of the human proteome. We introduce a network controllability-based method, OptiCon, for de...
15.
Taylor D, Aronow B, Tan K, Bernt K, Salomonis N, Greene C, et al.
Dev Cell
. 2019 Apr;
49(1):10-29.
PMID: 30930166
Single-cell gene expression analyses of mammalian tissues have uncovered profound stage-specific molecular regulatory phenomena that have changed the understanding of unique cell types and signaling pathways critical for lineage determination,...
16.
Mao G, Zhang Z, Fei F, Ding Y, Zhang W, Chen H, et al.
Int J Biol Macromol
. 2018 Oct;
121:930-935.
PMID: 30342137
GP11 had been reported to have effectively anti-tumor activity by improving the immune function in our previous study. To avoid drawbacks of the 5-Fu, GP11 in combination with 5-Fu was...
17.
Hu L, Pu L, Yang D, Zhang C, Wang H, Ding Y, et al.
Oncol Lett
. 2017 Nov;
14(5):5619-5623.
PMID: 29113191
The Philadelphia (Ph; BCR-ABL) chromosome originates from a translocation event between chromosomes 9 and 22, and results in the BCR-ABL fusion gene. In chronic myelogenous leukemia (CML), the BCR-ABL gene...
18.
Ding Y, Panzer J, Maris J, Castaneda A, Gomez-Chiari M, Mora J
Pediatr Blood Cancer
. 2017 Jul;
65(1).
PMID: 28748630
Immunotherapy with the anti-GD2 monoclonal antibody ch14.18, or dinutuximab, represents an important therapeutic advance in the treatment of pediatric high-risk neuroblastoma and is now considered part of standard of care...
19.
Xiong S, Pu L, Wang H, Hu L, Ding Y, Li M, et al.
Clin Chem Lab Med
. 2016 Jun;
55(1):82-90.
PMID: 27337741
Background: In the hematology department, the availability of biomarkers for early detection of infection is difficult to obtain. The present study aimed to compare the diagnostic values of neutrophil CD64...
20.
Raynard S, Zhao W, Bussen W, Lu L, Ding Y, Busygina V, et al.
J Biol Chem
. 2008 Apr;
283(23):15701-8.
PMID: 18390547
The BLAP75 protein combines with the BLM helicase and topoisomerase (Topo) IIIalpha to form an evolutionarily conserved complex, termed the BTB complex, that functions to regulate homologous recombination. BLAP75 binds...