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Journal of Translational Medicine

The Journal of Translational Medicine is a peer-reviewed open-access journal that focuses on the translation of scientific discoveries into clinical applications. It publishes high-quality research articles, reviews, and commentaries that bridge the gap between basic research and clinical practice, aiming to accelerate the development of innovative therapies and diagnostics for human diseases.
Details
Abbr. J Transl Med
Publisher Biomed Central
Start 2003
End Continuing
e-ISSN 1479-5876
Country United Kingdom
Language English
Specialties General Medicine
Biomedical Engineering
Metrics
h-index / Ranks: 1584 142
SJR / Ranks: 1732 1611
CiteScore / Ranks: 1162 11.00
JIF / Ranks: 780 7.4
Recent Articles
1.
F-box protein FBXO21 overexpression inhibits the proliferation and metastasis of clear cell renal cell carcinoma and is closely related to the CREB pathway and tumor immune cell infiltration
Yang W, Jing T, Wu C, Lu M, Yao X, Xia D, et al.
J Transl Med . 2025 Mar; 23(1):335. PMID: 40089779
Background: Many studies have shown that F-box proteins regulate epithelial-mesenchymal transition, which is closely related to tumor metastasis. However, there is still limited research on the role of F-box proteins...
2.
Gut Microbiome dysbiosis and immune activation correlate with somatic and neuropsychiatric symptoms in COVID-19 patients
Scalzo P, Marshall A, Soriano S, Curry K, Dulay M, Hodics T, et al.
J Transl Med . 2025 Mar; 23(1):327. PMID: 40087795
Background: Infection with SARS-CoV-2, the virus responsible for COVID-19, can lead to a range of physical symptoms and mental health challenges, including stress, anxiety, and depression. These effects are particularly...
3.
Short-term oral zinc supplementation enhances Natural Killer cell functionality and decreases circulating Innate Lymphoid Cell counts and frequencies in healthy young adults
Amling L, Rink L, Bennstein S
J Transl Med . 2025 Mar; 23(1):333. PMID: 40087783
Background: Zinc is an essential trace element with high importance for immune function. Previous research has shown that vegetarians and vegans are at increased risk of zinc deficiency, due to...
4.
Letter: Time to correct the record on the global burden of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Vardaman M, Gilmour S
J Transl Med . 2025 Mar; 23(1):331. PMID: 40087760
No abstract available.
5.
The NcRNA/Wnt axis in lung cancer: oncogenic mechanisms, remarkable indicators and therapeutic targets
Zhong Y, He J, Huang C, Lai H, Li X, Zheng C, et al.
J Transl Med . 2025 Mar; 23(1):326. PMID: 40087753
Early diagnosis of lung cancer (LC) is challenging, treatment options are limited, and treatment resistance leads to poor prognosis and management in most patients. The Wnt/β-catenin signaling pathway plays a...
6.
Correction to: Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via singlecell multiomics analysis
Sheng K, Chen J, Xu R, Sun H, Liu R, Wang Y, et al.
J Transl Med . 2025 Mar; 23(1):334. PMID: 40087752
No abstract available.
7.
Comprehensive review of the expanding roles of the carnitine pool in metabolic physiology: beyond fatty acid oxidation
Xiang F, Zhang Z, Xie J, Xiong S, Yang C, Liao D, et al.
J Transl Med . 2025 Mar; 23(1):324. PMID: 40087749
Traditionally, the carnitine pool is closely related to fatty acid metabolism. However, with increasing research, the pleiotropic effects of the carnitine pool have gradually emerged. The purpose of this review...
8.
Serum Uromodulin as early marker for ischemic acute kidney injury and nephron loss: association with kidney tissue distribution pattern
Vonbrunn E, Ebert N, Cordasic N, Amann K, Buttner A, Buttner-Herold M, et al.
J Transl Med . 2025 Mar; 23(1):323. PMID: 40087735
Background: Uromodulin (UMOD) is expressed in kidneys and is mainly excreted in the urine, although a smaller amount is also released into the serum. Here, we investigated UMOD in acute...
9.
Exposure of monocyte-derived macrophages to the UV-inactivated SARS-CoV-2 VOCs shows similar effects on the transcriptomic profile as active virus: a comparative analysis
Sammartino J, Vazzana R, Cuscino N, Castelbuono S, Giambruno R, Carcione C, et al.
J Transl Med . 2025 Mar; 23(1):332. PMID: 40087733
No abstract available.
10.
Integrating DNA and RNA sequencing for enhanced pathogen detection in respiratory infections
Gu D, Liu J, Wang J, Yi Y, Chu Y, Gao R, et al.
J Transl Med . 2025 Mar; 23(1):325. PMID: 40087699
Background: The clinical value of shotgun metagenomic next-generation sequencing (mNGS) in improving the detection rates of respiratory pathogens is well-established. However, mNGS is complex and expensive. This study designed and...