Weixue Wang
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Explore the profile of Weixue Wang including associated specialties, affiliations and a list of published articles.
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44
Citations
520
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Recent Articles
1.
Wang W, Liu Y, Du X, Wang H, Ai Y, Liu Q, et al.
Nat Commun
. 2025 Feb;
16(1):1623.
PMID: 39948342
Two-dimensional (2D) nanomaterials display unique characteristics owing to their ultrahigh surface-to-volume ratio and quantum confinement effects. Nonetheless, seeking a versatile and facile method to rationally shape ultrathin 2D frameworks is...
2.
Wang Y, Zhang X, Wang W, Zhang Y, Fleishman J, Wang H
Biol Direct
. 2025 Feb;
20(1):20.
PMID: 39920718
Cyclic GMP/AMP (cGAMP) synthase (cGAS), along with the endoplasmic reticulum (ER)-associated stimulator of interferon genes (STING), are crucial elements of the type 1 interferon response. cGAS senses microbial DNA and...
3.
Milgram B, Borrelli D, Brooijmans N, Henderson J, Hilbert B, Huff M, et al.
J Med Chem
. 2025 Jan;
68(3):2403-2421.
PMID: 39824516
After L858R and ex19del epidermal growth factor receptor (EGFR) mutations, ex20ins mutations are the third most common class of driver-mutations in non-small cell lung cancer (NSCLC). Unfortunately, first-, second-, and...
4.
Wang Y, Wang W, Zhang Y, Fleishman J, Wang H
Eur J Med Chem
. 2024 Dec;
283():117152.
PMID: 39657462
Sepsis-associated acute lung injury (SALI) is a common complication of sepsis, consisting of a dysfunctional host response to infection-mediated heterogenous complexes. SALI is reported in up to 50 % of...
5.
Wang H, Fleishman J, Cheng S, Wang W, Wu F, Wang Y, et al.
Mol Cancer
. 2024 Aug;
23(1):177.
PMID: 39192329
The development of drug resistance remains a major challenge in cancer treatment. Ferroptosis, a unique type of regulated cell death, plays a pivotal role in inhibiting tumour growth, presenting new...
6.
Wang M, Liang Y, Qin Y, Ma R, Yu H, Wang W, et al.
Curr Pharm Des
. 2024 Aug;
30(36):2896-2910.
PMID: 39136516
Background: Diabetic cardiomyopathy (DCM) is a common diabetes complication with limited medications. Gegen Qinlian decoction (GQD) has been used in the treatment of diabetes and its related complications in China...
7.
DeRatt L, Zhang Z, Pietsch C, Cisar J, Zhang X, Wang W, et al.
J Med Chem
. 2024 Jun;
67(13):11254-11272.
PMID: 38889244
Acute myelogenous leukemia (AML), a heterogeneous disease of the blood and bone marrow, is characterized by the inability of myeloblasts to differentiate into mature cell types. Dihydroorotate dehydrogenase (DHODH) is...
8.
DeRatt L, Pietsch E, Cisar J, Jacoby E, Kazmi F, Matico R, et al.
ACS Med Chem Lett
. 2024 Mar;
15(3):381-387.
PMID: 38505861
Dihydroorotate dehydrogenase (DHODH) is a mitochondrial enzyme that affects many aspects essential to cell proliferation and survival. Recently, DHODH has been identified as a potential target for acute myeloid leukemia...
9.
Duan J, Zhu L, Shi Y, Wang W, Wang T, Ning T, et al.
BMC Cancer
. 2024 Mar;
24(1):302.
PMID: 38443891
Background: There are various recommendations for third-line treatment in mCRC, however, there is no consensus on who is more suitable for particular strategy. Chemotherapy re-use in third-line setting is a...
10.
Wang W, Wang T, Zhang Y, Deng T, Zhang H, Ba Y
Oncol Res
. 2024 Feb;
32(3):489-502.
PMID: 38370339
Different from necrosis, apoptosis, autophagy and other forms of cell death, ferroptosis is a mechanism that catalyzes lipid peroxidation of polyunsaturated fatty acids under the action of iron divalent or...